Aguilera-Lopez, Andres;Gómez-González, Belén:
Break-induced RNA-DNA hybrids (BIRDHs) in homologous recombination: friend or foe?. Embo Reports. 2023. Vol: 24. Núm: 12. Pág. e57801-e57801.
Garcia-Rubio, Maria Luisa;Gómez-González, Belén;Aguilera-Lopez, Andres:
The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts. Nature Communications. 2023. Vol: 14. Núm: 1. Pág. 6890-6890. https://doi.org/10.1093/genetics/iyac108.
Barroso-Ceballos, Sonia Ines;Perez, Carmen;Garcia-Rubio, Maria Luisa;Gómez-González, Belén;Aguilera-Lopez, Andres:
DICER ribonuclease removes harmful R-loops. Molecular Cell. 2023. Vol: 83. Núm: 20. Pág. 3707 -3719.e5.
Martínez, Juan Carlos;Garcia-Rubio, Maria Luisa;Garcia, Alicia;Antequera, Francisco ;Gómez-González, Belén;Aguilera-Lopez, Andres:
A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability. Genetics. 2022. 10.1093/genetics/iyac108.
Sessa, Gaetana;Martinez, Juan S;Lombard, Berangere;Loew, Damarys;Vagner, Stephan;Aguilera-Lopez, Andres;Carreira, Aura;Gómez-González, Belén;Silva, Sonia;Perez-calero, Carmen;Beaurepere, Romane;Barroso-Ceballos, Sonia Ines;Martineau, Sylvain;Martin, Charlotte;Ehlen, Asa:
BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair. EMBO Journal. 2021. 10.15252/embj.2020106018.
Ortega, Pedro;Mérida, José Antonio;García-Rondón, Ana;Gómez-González, Belén;Aguilera-Lopez, Andres:
DNA-RNA hybrids at DSBs interfere with repair by homologous recombination.. eLife. 2021. Vol: 10.
Gómez-González, Belén;Sessa, G;Carreira, A;Aguilera-Lopez, Andres:
A new interaction between BRCA2 and DDX5 promotes the repair DNA breaks at transcribed chromatin.. Molecular and Cellular Oncology. 2021. Vol: 8. Núm: 3.
LAFUENTE-BARQUERO, JUAN FRANCISCO;Garcia-Rubio, Maria Luisa;San Martin-Alonso, Marta;Gómez-González, Belén;Aguilera-Lopez, Andres:
Harmful DNA: RNA hybrids are formed in cis and in a RAD51-independent manner. eLife. 2020. Vol: 9:e56674.
Ortega, Pedro;García -Pichardo, Desiré;San Martin-Alonso, Marta;García-Rondón, Ana;Gómez-González, Belén;Aguilera-Lopez, Andres:
Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage. Microbial cell. 2020. Vol: 7. Pág. 190-198. 10.15698/mic2020.07.723.
Gómez-González, Belén;Barroso-Ceballos, Sonia Ines;Herrera-Moyano, Emilia;Aguilera-Lopez, Andres:
Spontaneous DNA-RNA hybrids: differential impacts throughout the cell cycle. Cell Cycle. 2020. Vol: 19. Núm: (5). Pág. 525-531. 10.1080/15384101.2020.
Gómez-González, Belén;Aguilera-Lopez, Andres:
Looping the (R) Loop in DSB REpair via RNA Methylation. Molecular Cell. 2020. Vol: 79.
Gómez-González, Belén;Ortega, Pedro;Aguilera-Lopez, Andres:
Histone deacetylases facilitate the accurate repair of broken forks.. Molecular and Cellular Oncology. 2020. Vol: 7. Núm: (2). 10.1080/23723556.2019.1705731..
Ortega, Pedro;Gómez-González, Belén;Aguilera-Lopez, Andres:
Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion.. Nature Communications. 2019. Vol: 10. Núm: 1. 10.1038/s41467-019-13210-5.
Gómez-González, Belén;Aguilera-Lopez, Andres:
Transcription-mediated replication hindrance: a major driver of genome instability. Genes & Development. 2019. Vol: 33. Núm: 15-16. Pág. 1008-1026. 10.1101/gad.324517.119.
Barroso-Ceballos, Sonia Ines;Herrera-Moyano, Emilia;Muñoz, Sergio;Garcia-Rubio, Maria Luisa;Gómez-González, Belén;Aguilera-Lopez, Andres:
The DNA damage response acts as a safeguard against harmful DNA-RNA hybrids of different origins. Embo Reports. 2019. Vol: 20. doi.org/10.15252/embr.201847250.
Gómez-González, Belén;Patel, Harshil;Early, Anne;Diffley, John:
Rpd3L Contributes to the DNA Damage Sensitivity of Saccharomyces cerevisiae Checkpoint Mutants.. Genetics. 2019. 10.1534/genetics.118.301817.
Gómez-González, Belén:
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial cell. 2019. Vol: 6. Núm: 1. Pág. 1-64. 10.15698/mic2019.01.664.
BHATIA, VAIBHAV;Herrera-Moyano, Emilia;Herrera-Moyano, Emilia;Aguilera-Lopez, Andres;Gómez-González, Belén:
The Role of Replication-Associated Repair Factors on R-Loops. Genes. 2017. Vol: 8. Núm: 7. 10.3390/genes8070171.
García -Pichardo, Desiré;Martínez, Juan Carlos;Garcia-Rubio, Maria Luisa;Gómez-González, Belén;García-Rondón, Ana;Aguilera-Lopez, Andres:
Histone Mutants Separate R Loop Formation from Genome Instability Induction. Molecular Cell. 2017. Vol: 66. Núm: 5. Pág. 597-609. 10.1016/j.molcel.2017.05.014.
Gómez-González, Belén;Aguilera-Lopez, Andres:
The need to regulate replication fork speed. Science. 2017. Vol: 358. Núm: 6364. Pág. 722-723. 10.1126/science.aaq0678 .
Lafuente-barquero, Juan ;Luke, Brian;Luke-glaser, Sarah ;Graf, Marco ;Pinela, Sónia Cristina;Gómez-González, Belén;Lockhart, Arianna ;Lisby, Michael;Aguilera-Lopez, Andres:
The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage. PLoS Genetics. 2017. Vol: 13. Núm: 12. Pág. 1007136-1007136. 10.1371/journal.pgen.1007136.
Muñoz-Galvan, Sandra;Garcia-Rubio, Maria Luisa;Ortega, Pedro;Ruiz-Perez, Jose Francisco;Jimeno-Gonzalez, Sonia;Pardo-, Benjamín;Gómez-González, Belén;Aguilera-Lopez, Andres:
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination. PLoS Genetics. 2017. Vol: 13. Núm: 3.
Aguilera-Lopez, Andres;Gómez-González, Belén:
DNA-RNA hybrids: the risks of DNA breakage during transcription. Nature Structural and Molecular Biology. 2017. Vol: 24. Núm: 5. Pág. 439-443.
Yekezare, Mona;Gómez-González, Belén;Diffley, John:
Controlling DNA replication origins in response to DNA damage - inhibit globally, activate locally.. Journal of Cell Science. 2013. Vol: 126. Pág. 1297-1306.
Domínguez-Sánchez, María Salud;Barroso-Ceballos, Sonia Ines;Gómez-González, Belén;Luna-Varo, Rosa Maria;Aguilera-Lopez, Andres:
Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.. PLoS Genetics. 2011. Vol: 7. Núm: 12. Pág. e1002386-e1002385. 10.1371/journal.pgen.1002386.
Bermejo-,Rodrigo;Capra-,Thelma;Aguilera-Lopez, Andres;Katou-,Yuki;Shirahige-,K;Foiani-,Marco;Jossen-,Rachel;Colosio-,Arianna;Frattini-,Camilla;Carotenuto-,Walter;Cocito-,Andrea;Doksani-,Ylli;Klein-,H.L.;Gómez-González, Belén:
THE REPLICATION CHECKPOINT PROTECTS FORK STABILITY BY RELEASING TRANSCRIBED GENES FROM NUCLEAR PORES.. Cell. 2011. Vol: 146. Pág. 233-246.
Gómez-González, Belén;Garcia-Rubio, Maria Luisa;Bermejo-,R;Gaillard-, Helene;Shirahige-,K;Marin-Rodriguez, Antonio;Foiani, Marco;Aguilera-Lopez, Andres:
GENOME-WIDE FUNCTION OF THO/TREX IN ACTIVE GENES PREVENTS R-LOOP-DEPENDENT REPLICATION OBSTACLES. EMBO Journal. 2011. Vol: 30. Núm: 15. Pág. 3106-3119.
Ruiz-Perez, Jose Francisco;Gómez-González, Belén;Aguilera-Lopez, Andres:
AID INDUCES DOUBLE-STRAND BREAKS AT IMMUNOGLOBULIN SWITCH REGIONS AND C-MYC CAUSING CHROMOSOMAL TRANSLOCATIONS IN YEAST THO MUTANTS.. PLoS Genetics. 2011. Vol: 7. Núm: 2. Pág. E1002009-0.
Mischo-,Hannah;Gómez-González, Belén;Grzechnik-,Pawel;García-Rondón, Ana;Wei-,Wu;Steinmetz-,Lars;Aguilera-Lopez, Andres;Proudfoot-J,Nicholas:
YEAST SEN1 HELICASE PROTECTS THE GENOME FROM TRANSCRIPTION-ASSOCIATED INSTABILITY. Molecular Cell. 2011. Vol: 41. Pág. 21-32.
Pardo-, Benjamín;Gómez-González, Belén;Aguilera-Lopez, Andres:
DNA DOUBLE-STRAND BREAK REPAIR: HOW TO FIX A BROKEN RELATIONSHIP. Cellular and Molecular Life Sciences. 2009. Vol: 66. Núm: 6. Pág. 1039-1056.
Gómez-González, Belén;Felipe-Abrio, Irene;Aguilera-Lopez, Andres:
THE S-PHASE CHECKPOINT IS REQUIRED TO RESPOND TO R-LOOPS ACCUMULATED IN THO MUTANTS. Molecular and Cellular Biology. 2009. Vol: 29. Núm: 19. Pág. 5203-5213.
Gómez-González, Belén;Aguilera-Lopez, Andres:
R-LOOPS DO NOT ACCUMULATE IN TRANSCRIPTION-DEFECTIVE HPR1-101 MUTANTS: IMPLICATIONS FOR THE FUNCTIONAL ROLE OF THO/TREX. Nucleic Acids Research. 2009. Vol: 37. Núm: 13. Pág. 4315-4321.
Ruiz-Perez, Jose Francisco;Gómez-González, Belén;Aguilera-Lopez, Andres:
CHROMOSOMAL TRANSLOCATIONS CAUSED BY EITHER POL32-DEPENDANT OR INDEPENDANT TRIPARENTAL BREAK-INDUCED REPLICATION. Molecular and Cellular Biology. 2009. Vol: 29. Núm: 20. Pág. 5441-5454.
Aguilera-Lopez, Andres;Gómez-González, Belén:
GENOME INSTABILITY: A MECHANISTIC VIEW OF ITS CAUSES AND CONSEQUENCES. Nature Reviews. Genetics. 2008. Vol: 9. Núm: 3. Pág. 204-217.
González-Aguilera, Cristina;Tous-Rivera, Cristina;Gómez-González, Belén;Huertas-Sanchez, Pablo;Luna-Varo, Rosa Maria;Aguilera-Lopez, Andres:
THE THP1-SAC3-SUS1-CDC31 COMPLEX WORKS IN TRANSCRIPTION ELONGATION-MRNA EXPORT PREVENTING RNA-MEDIATED GENOME INSTABILITY. Molecular Biology of the Cell. 2008. Vol: 19. Núm: 10. Pág. 4310-4318.
Gómez-González, Belén;Aguilera-Lopez, Andres:
ACTIVATION-INDUCED CYTIDINE DEAMINASE ACTION IS STRONGLY STIMULATED BY MUTATIONS OF THE THO COMPLEX. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2007. Vol: 104. Núm: 20. Pág. 8409-8414.