Directorio
JUAN MANUEL PEREZ RUIZ
Categoría
Profesor Titular de Universidad
Contacto
Correo electrónico
Departamento
Área
Bioquímica y Biología Molecular
Docencia
Asignaturas que imparte
Investigación
Grupo de investigación
BIOTECNOLOGÍA DE SEMILLAS DE CEREALES (BIOSEM)
Proyectos y contratos de investigación
CONTROL HORMONAL DE LA EXPRESIÓN GÉNICA EN PLANTAS EN RESPUESTAS A ESTRÉS ABIÓTICO Y CONDICIONES NUTRICIONALES (BMC2001-2366-C03-01 - Investigador/a)
EL SISTEMA NADP/TIORREDOXINA COMO MEDIO PARA LA IDENTIFICACIÓN DE GENES DE RESPUESTA A ESTRÉS OXIDATIVO EN PLANTAS (BIO2004-02023 - Investigador/a)
33. METABOLIC CONTROL OF PLANT GROWTH (HA2005-0067 - Investigador/a)
IDENTIFICACIÓN DE GENES IMPLICADOS EN EL BALANCE ENTRE ASIMILACIÓN DE CARBONO Y RESPUESTA FRENTE A DAÑO OXIDATIVO EN PLANTAS (P06-CVI-01578 - Investigador/a)
Regulación Redox del Metabolismo Fotosintético del Cloroplasto (BIO2017-85195-C2-1-P - Investigador/a)
Función de Ntrc en la Regulación Redox de Cloroplastos: Relación con el Sistema Dependiente de Ferredoxinas e Implicaciones en Señalización en Plantas (BIO2013-43556-P - Investigador/a)
Asistencia a congresos
Puerto-Galán, Leonor;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
Control 2-Cys peroxiredoxin overoxidation in Arabidopsis. The role of NTRC and Sulfiredoxin.. Poster en Congreso. XIII Congresso Luso-Espanhol de Fisiología Vegetal.. LISBOA. PORTUGAL. 2013
Control 2-Cys peroxiredoxin overoxidation in Arabidopsis. The role of NTRC and Sulfiredoxin.. Poster en Congreso. XIII Congresso Luso-Espanhol de Fisiología Vegetal.. LISBOA. PORTUGAL. 2013
Pérez-Ruíz, Juan Manuel;Spinola-Minguez, Maria Cristina;Kirchsteiger-, Kerstin;Cejudo-Fernández, Francisco Javier:
UN NUEVO SISTEMA REDOX DE ALTA EFICIENCIA PARA LA PROTECCIÓN DEL CLOROPLASTO FRENTE A DAÑO OXIDATIVO. Comunicación en congreso. VIIIREUNIÓN DE BIOLOGÍA MOLECULAR DE PLANTAS () (.2006.PAMPLONA). PAMPLONA. 2006
UN NUEVO SISTEMA REDOX DE ALTA EFICIENCIA PARA LA PROTECCIÓN DEL CLOROPLASTO FRENTE A DAÑO OXIDATIVO. Comunicación en congreso. VIIIREUNIÓN DE BIOLOGÍA MOLECULAR DE PLANTAS () (.2006.PAMPLONA). PAMPLONA. 2006
Pulido-Gómez, Pablo;Cazalis-, Roland;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
CLONACIÓN Y CARACTERIZACIÓN DE TRES TIORREDOXINAS H DE TRIGO QUE MUESTRAN EXPRESIÓN DIFERENCIAL EN SEMILLAS. Comunicación en congreso. VIIIREUNIÓN DE BIOLOGÍA MOLECULAR DE PLANTAS () (.2006.PAMPLONA). PAMPLONA. 2006
CLONACIÓN Y CARACTERIZACIÓN DE TRES TIORREDOXINAS H DE TRIGO QUE MUESTRAN EXPRESIÓN DIFERENCIAL EN SEMILLAS. Comunicación en congreso. VIIIREUNIÓN DE BIOLOGÍA MOLECULAR DE PLANTAS () (.2006.PAMPLONA). PAMPLONA. 2006
Pérez-Ruíz, Juan Manuel;Spinola-Minguez, Maria Cristina;Kirschteiger-,Kerstin;Pulido-Gómez, Pablo;Cejudo-Fernández, Francisco Javier:
NTRC IS AN NTR-THIOREDOXIN SYSTEM IN A SINGLE POLYPEPTIDE ESSENTIAL FOR CHLOROPLAST DETOXIFICATION. Comunicación en congreso. REDOXINS AND RELATED PROTEINS () (.2005.AUSSOIS (FRANCIA)). AUSSOIS (FRANCIA). 2005
NTRC IS AN NTR-THIOREDOXIN SYSTEM IN A SINGLE POLYPEPTIDE ESSENTIAL FOR CHLOROPLAST DETOXIFICATION. Comunicación en congreso. REDOXINS AND RELATED PROTEINS () (.2005.AUSSOIS (FRANCIA)). AUSSOIS (FRANCIA). 2005
Pérez-Ruíz, Juan Manuel;Spinola-Minguez, Maria Cristina;Kirchsteiger-, Kerstin;Pulido-Gómez, Pablo;Cejudo-Fernández, Francisco Javier:
NTRC IS AN NTR-THIOREDOXIN SYSTEM IN A SINGLE POLYPEPTIDE ESSENTIAL FOR CHLOROPLAST DETOXIFICATION.. Ponencia en Congreso. REDOXINS AND RELATED PROTEINS () (.2005.AUSSOIS (FRANCIA)). AUSSOIS (FRANCIA). 2005
NTRC IS AN NTR-THIOREDOXIN SYSTEM IN A SINGLE POLYPEPTIDE ESSENTIAL FOR CHLOROPLAST DETOXIFICATION.. Ponencia en Congreso. REDOXINS AND RELATED PROTEINS () (.2005.AUSSOIS (FRANCIA)). AUSSOIS (FRANCIA). 2005
Pérez-Ruíz, Juan Manuel;Serrato-Recio, Antonio Jesús;Spinola-Minguez, Maria Cristina;Cejudo-Fernández, Francisco Javier:
UN NUEVO TIPO DE NADPH TIORREDOXINA REDUCTASA, DE LOCALIZACIÓN CLOROPLÁSTICA, CUYA DEFICIENCIA CAUSA HIPERSENSIBILIDAD FRENTE A ESTRÉS ABIÓTICO EN ARA. Ponencia en Congreso. REUNIÓN DE BIOLOGÍA MOLECULAR DE PLANTAS (7.2004.BENALMÁDENA, MÁLAGA). BENALMÁDENA, MÁLAGA. 2004
UN NUEVO TIPO DE NADPH TIORREDOXINA REDUCTASA, DE LOCALIZACIÓN CLOROPLÁSTICA, CUYA DEFICIENCIA CAUSA HIPERSENSIBILIDAD FRENTE A ESTRÉS ABIÓTICO EN ARA. Ponencia en Congreso. REUNIÓN DE BIOLOGÍA MOLECULAR DE PLANTAS (7.2004.BENALMÁDENA, MÁLAGA). BENALMÁDENA, MÁLAGA. 2004
Serrato-Recio, Antonio Jesús;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
THE NUCLEAR LOCALIZATION OF TYPE-H THIOREDOXINS IN WHEAT SEED TISSUES SUFFERNIG OXIDATIVE STRESS SUGGESTS A ROLE OF THE NADPH/THIOREDOXIN SYSTEM IN TH. Comunicación en congreso. GOEDON RESEARCH CONFERENCE ON STRESS-INDUCED GENE EXPRESSION (.2003.OXFORD (INGLATERRA)). OXFORD (INGLATERRA). 2003
THE NUCLEAR LOCALIZATION OF TYPE-H THIOREDOXINS IN WHEAT SEED TISSUES SUFFERNIG OXIDATIVE STRESS SUGGESTS A ROLE OF THE NADPH/THIOREDOXIN SYSTEM IN TH. Comunicación en congreso. GOEDON RESEARCH CONFERENCE ON STRESS-INDUCED GENE EXPRESSION (.2003.OXFORD (INGLATERRA)). OXFORD (INGLATERRA). 2003
Artículos publicados
Ojeda, Valle;Jiménez-lópez, Julia;Romero-Campero, Francisco José;Cejudo-Fernández, Francisco Javier;Pérez-Ruíz, Juan Manuel:
A chloroplast redox relay adapts plastid metabolism to light and affects cytosolic protein quality control. Plant Physiology. 2021. Vol: 0. Pág. 1-15. https://doi.org/10.1093/plphys/kiab246.
A chloroplast redox relay adapts plastid metabolism to light and affects cytosolic protein quality control. Plant Physiology. 2021. Vol: 0. Pág. 1-15. https://doi.org/10.1093/plphys/kiab246.
Cejudo-Fernández, Francisco Javier;Ojeda, Valle;Delgado, Víctor;Gonzalez-García, María De La Cruz;Pérez-Ruíz, Juan Manuel:
Chloroplast Redox Regulatory Mechanisms in Plant Adaptation to Light and Darkness. Frontiers in Plant Science. 2019. 10.3389/fpls.2019.00380.
Chloroplast Redox Regulatory Mechanisms in Plant Adaptation to Light and Darkness. Frontiers in Plant Science. 2019. 10.3389/fpls.2019.00380.
Ojeda, Valle;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
The NADPH-dependent thioredoxin reductase C-2-Cys peroxiredoxin redox system modulates the activity of thioredoxin x in Arabidopsis chloroplasts. Plant and Cell Physiology. 2018. Vol: 59. Núm: 10. Pág. 2155-2164. 10.1093/pcp/pcy134.
The NADPH-dependent thioredoxin reductase C-2-Cys peroxiredoxin redox system modulates the activity of thioredoxin x in Arabidopsis chloroplasts. Plant and Cell Physiology. 2018. Vol: 59. Núm: 10. Pág. 2155-2164. 10.1093/pcp/pcy134.
Ojeda, Valle;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
2-Cys peroxiredoxins participate in the oxidation of chloroplast enzymes in the dark. Molecular Plant. 2018. Vol: 11. Pág. 1377-1388. 10.1016/j.molp.2018.09.005.
2-Cys peroxiredoxins participate in the oxidation of chloroplast enzymes in the dark. Molecular Plant. 2018. Vol: 11. Pág. 1377-1388. 10.1016/j.molp.2018.09.005.
Richter, Andreas;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier;Grimm, Bernhard:
The control of chlorophyll biosynthesis mainly depends on thioredoxins. FEBS Letters. 2018. Vol: 592. Núm: 18. Pág. 3111-3115. 10.1002/1873-3468.13216.
The control of chlorophyll biosynthesis mainly depends on thioredoxins. FEBS Letters. 2018. Vol: 592. Núm: 18. Pág. 3111-3115. 10.1002/1873-3468.13216.
Ojeda, Valle;Pérez-Ruíz, Juan Manuel;Gonzalez-García, María De La Cruz;Nájera, Victoria A.;Sahrawy-Barragan, Mariam;Serrato, Antonio J.;Geigenberger, Peter;Ojeda, Valle;Cejudo-Fernández, Francisco Javier:
NADPH thioredoxin reductase C and thioredoxins act concertedly in seedling development. Plant Physiology. 2017. Pág. 1436-1448. 10.1104/pp.17.00481.
NADPH thioredoxin reductase C and thioredoxins act concertedly in seedling development. Plant Physiology. 2017. Pág. 1436-1448. 10.1104/pp.17.00481.
Ojeda, Valle;Nájera, Victoria A.;Gonzalez-García, María De La Cruz;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
Photosynthetic activity of cotyledons is critical during post-germinative growth and seedling establishment. Plant Signaling & Behavior. 2017. Vol: 12. 10.1080/15592324.2017.1347244.
Photosynthetic activity of cotyledons is critical during post-germinative growth and seedling establishment. Plant Signaling & Behavior. 2017. Vol: 12. 10.1080/15592324.2017.1347244.
Pérez-Ruíz, Juan Manuel;Naranjo-, Belén;Ojeda, Valle;Guinea-Díaz, Manuel;Cejudo-Fernández, Francisco Javier:
The NTRC-dependent redox balance of 2-Cys peroxiredoxins is needed for optimal function of the photosynthetic apparatus. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017. Vol: 114. Núm: 45. Pág. 12069-12074. 10.1073/pnas.1706003114.
The NTRC-dependent redox balance of 2-Cys peroxiredoxins is needed for optimal function of the photosynthetic apparatus. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017. Vol: 114. Núm: 45. Pág. 12069-12074. 10.1073/pnas.1706003114.
Nájera, Victoria A.;Gonzalez-García, María De La Cruz;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
An event of alternative splicing affects the expression of the NTRC gene, encoding NADPH-thioredoxin reductase C, in seed plants. Plant Science. 2017. Vol: 258. Pág. 21-28. doi: 10.1016/j.plantsci.2017.02.001.
An event of alternative splicing affects the expression of the NTRC gene, encoding NADPH-thioredoxin reductase C, in seed plants. Plant Science. 2017. Vol: 258. Pág. 21-28. doi: 10.1016/j.plantsci.2017.02.001.
Puerto-Galán, Leonor;Pérez-Ruíz, Juan Manuel;Guinea, Manuel;Cejudo-Fernández, Francisco Javier:
The contribution of NADPH thioredoxin reductase C (NTRC) and sulfiredoxin to 2-Cys peroxiredoxin overoxidation in Arabidopsis thaliana chloroplasts. Journal of Experimental Botany. 2015. Vol: 66. Núm: 10. Pág. 2957-2966. 10.1093/jxb/eru512..
The contribution of NADPH thioredoxin reductase C (NTRC) and sulfiredoxin to 2-Cys peroxiredoxin overoxidation in Arabidopsis thaliana chloroplasts. Journal of Experimental Botany. 2015. Vol: 66. Núm: 10. Pág. 2957-2966. 10.1093/jxb/eru512..
Pérez-Ruíz, Juan Manuel;Guinea-Díaz, Manuel;Puerto-Galán, Leonor;Cejudo-Fernández, Francisco Javier:
NADPH THIOREDOXIN REDUCTASE C IS INVOLVED IN REDOX REGULATION OF THE MG-CHELATASE I SUBUNIT IN ARABIDOPSIS THALIANA CHLOROPLASTS. Molecular Plant. 2014. Vol: 7. Pág. 1252-1255. 10.1093/mp/ssu032.
NADPH THIOREDOXIN REDUCTASE C IS INVOLVED IN REDOX REGULATION OF THE MG-CHELATASE I SUBUNIT IN ARABIDOPSIS THALIANA CHLOROPLASTS. Molecular Plant. 2014. Vol: 7. Pág. 1252-1255. 10.1093/mp/ssu032.
Bernal-Bayard, Pilar Del Carmen;Ojeda, Valle;Hervás-Morón, Manuel;Cejudo-Fernández, Francisco Javier;Navarro-Carruesco, José Antonio;Velázquez-campoy, Adrián;Pérez-Ruíz, Juan Manuel;Ojeda, Valle:
Molecular recognition in the interaction of chloroplast 2-Cys peroxiredoxin with NADPH-thioredoxin reductase C (NTRC) and thioredoxin x. FEBS Letters. 2014. Vol: 588. Pág. 4342-4347. http://dx.doi.org/10.1016/j.febslet.2014.09.044.
Molecular recognition in the interaction of chloroplast 2-Cys peroxiredoxin with NADPH-thioredoxin reductase C (NTRC) and thioredoxin x. FEBS Letters. 2014. Vol: 588. Pág. 4342-4347. http://dx.doi.org/10.1016/j.febslet.2014.09.044.
Woodson, Jesse;Pérez-Ruíz, Juan Manuel;Schmitz, Rj;Ecker, J;Chory, Joanne:
SIGMA FACTOR-MEDIATED PLASTID RETROGRADE SIGNALS CONTROL NUCLEAR GENE EXPRESSION. The Plant Journal. 2013. Vol: 73. Pág. 1-13.
SIGMA FACTOR-MEDIATED PLASTID RETROGRADE SIGNALS CONTROL NUCLEAR GENE EXPRESSION. The Plant Journal. 2013. Vol: 73. Pág. 1-13.
Puerto-Galán, Leonor;Pérez-Ruíz, Juan Manuel;Ferrandez-Navarro, Julia;Cano-Ruiz, Beatriz;Naranjo-, Belén;Nájera, Victoria A.;Gonzalez-García, María De La Cruz;Lindahl-, Anna Marika;Cejudo-Fernández, Francisco Javier:
Overoxidation of chloroplast 2-Cys peroxiredoxins: balancing toxic and signaling activities of hydrogen peroxide. Frontiers in Plant Science. 2013. Vol: 4. 10.3389/fpls.2013.00310 .
Overoxidation of chloroplast 2-Cys peroxiredoxins: balancing toxic and signaling activities of hydrogen peroxide. Frontiers in Plant Science. 2013. Vol: 4. 10.3389/fpls.2013.00310 .
Gilkerson, J;Pérez-Ruíz, Juan Manuel;Chory, Joanne ;Callis, Judy:
THE PLASTID-LOCALIZED PFKB-TYPE CARBOHYDRATE KINASES FRUCTOKINASE-LIKE 1 AND 2 ARE ESSENTIAL FOR GROWTH AND DEVELOPMENT OF ARABIDOPSIS THALIANA. BMC Plant Biology. 2012. Vol: 12. 10.1186/1471-2229-12-102.
THE PLASTID-LOCALIZED PFKB-TYPE CARBOHYDRATE KINASES FRUCTOKINASE-LIKE 1 AND 2 ARE ESSENTIAL FOR GROWTH AND DEVELOPMENT OF ARABIDOPSIS THALIANA. BMC Plant Biology. 2012. Vol: 12. 10.1186/1471-2229-12-102.
Woodson, Jesse;Pérez-Ruíz, Juan Manuel;Chory, Joanne:
HEME SYNTHESIS BY PLASTID FERROCHELATASE I REGULATES NUCLEAR GENE EXPRESSION IN PLANTS. Current Biology. 2011. Vol: 21. Pág. 897-903. 10.1016/j.cub.2011.04.004.
HEME SYNTHESIS BY PLASTID FERROCHELATASE I REGULATES NUCLEAR GENE EXPRESSION IN PLANTS. Current Biology. 2011. Vol: 21. Pág. 897-903. 10.1016/j.cub.2011.04.004.
Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
A PROPOSED REACTION MECHANISM FOR RICE NADPH THIOREDOXIN REDUCTASE C, AN ENZYME WITH PROTEIN DISULFIDE REDUCTASE ACTIVITY. FEBS Letters. 2009. Vol: 583. Pág. 1399-1402.
A PROPOSED REACTION MECHANISM FOR RICE NADPH THIOREDOXIN REDUCTASE C, AN ENZYME WITH PROTEIN DISULFIDE REDUCTASE ACTIVITY. FEBS Letters. 2009. Vol: 583. Pág. 1399-1402.
Pérez-Ruíz, Juan Manuel;Gonzalez-García, María De La Cruz;Spinola-Minguez, Maria Cristina;Sandalio-,L.M.;Cejudo-Fernández, Francisco Javier:
THE CUATERNARY STRUCTURE OF NADPH THIOREDOXIN REDUCTASE C IS REDOX SENSITIVE. Molecular Plant. 2009. Vol: 2. Núm: 3. Pág. 457-467. http://dx.doi.org/10.1093/mp/ssp011.
THE CUATERNARY STRUCTURE OF NADPH THIOREDOXIN REDUCTASE C IS REDOX SENSITIVE. Molecular Plant. 2009. Vol: 2. Núm: 3. Pág. 457-467. http://dx.doi.org/10.1093/mp/ssp011.
Spinola-Minguez, Maria Cristina;Pérez-Ruíz, Juan Manuel;Kirchsteiger-, Kerstin;Pulido-Gómez, Pablo;Gonzalez-García, María De La Cruz;Cejudo-Fernández, Francisco Javier:
NTRC NEW WAYS OF USING NADPH IN THE CHLOROPLAST. Physiologia Plantarum. 2008. Vol: 133. Núm: 3. Pág. 516-524.
NTRC NEW WAYS OF USING NADPH IN THE CHLOROPLAST. Physiologia Plantarum. 2008. Vol: 133. Núm: 3. Pág. 516-524.
Cazalis-, Roland;Pulido-Gómez, Pablo;Aussenac-,Tierry;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
CLONING AND CHARACTERIZATION OF THREE THIOREDOXIN H ISOFORMS FROM WHEAT SHOWING DIFFERENTIAL EXPRESSION IN SEEDS. Journal of Experimental Botany. 2006. Vol: 57. Núm: 10. Pág. 2165-2172.
CLONING AND CHARACTERIZATION OF THREE THIOREDOXIN H ISOFORMS FROM WHEAT SHOWING DIFFERENTIAL EXPRESSION IN SEEDS. Journal of Experimental Botany. 2006. Vol: 57. Núm: 10. Pág. 2165-2172.
Pérez-Ruíz, Juan Manuel;Spinola-Minguez, Maria Cristina;Kirchsteiger-, Kerstin;Kirschteiger-,Kerstin;Moreno-Onorato, Francisco Javier;Moreno-, Francisco Javier;Sahrawy-Barragan, Mariam;Cejudo-Fernández, Francisco Javier:
RICE NTRC IS A HIGH-EFFICIENCY REDOX SYSTEM FOR CHLOROPLAST PROTECTION AGAINST OXIDATIVE DAMAGE. The Plant Cell. 2006. Vol: 18. Núm: 9. Pág. 2356-2368.
RICE NTRC IS A HIGH-EFFICIENCY REDOX SYSTEM FOR CHLOROPLAST PROTECTION AGAINST OXIDATIVE DAMAGE. The Plant Cell. 2006. Vol: 18. Núm: 9. Pág. 2356-2368.
Serrato-Recio, Antonio Jesús;Pérez-Ruíz, Juan Manuel;Spinola-Minguez, Maria Cristina;Cejudo-Fernández, Francisco Javier:
A NOVEL NADPH THIOREDOXIN REDUCTASE, LOCALIZED IN THE CHLOROPLAST, WHICH DEFICIENCY CAUSES HYPERSENSITIVITY TO ABIOTIC STRESS IN ARABIDOPSIS THALIANA. Journal of Biological Chemistry. 2004. Vol: 279. Núm: 42. Pág. 43821-43827.
A NOVEL NADPH THIOREDOXIN REDUCTASE, LOCALIZED IN THE CHLOROPLAST, WHICH DEFICIENCY CAUSES HYPERSENSITIVITY TO ABIOTIC STRESS IN ARABIDOPSIS THALIANA. Journal of Biological Chemistry. 2004. Vol: 279. Núm: 42. Pág. 43821-43827.
Serrato-Recio, Antonio Jesús;Pérez-Ruíz, Juan Manuel;Cejudo-Fernández, Francisco Javier:
CLONING OF THIOREDOXIN H REDUCTASE AND CHARACTERIZATION OF THE THIOREDOXIN REDUCTASE-THIOREDOXIN H SYSTEM FROM WHEAT. Biochemical Journal. 2002. Vol: 367. Pág. 491-497.
CLONING OF THIOREDOXIN H REDUCTASE AND CHARACTERIZATION OF THE THIOREDOXIN REDUCTASE-THIOREDOXIN H SYSTEM FROM WHEAT. Biochemical Journal. 2002. Vol: 367. Pág. 491-497.
Cejudo-Fernández, Francisco Javier;Gonzalez-García, María De La Cruz;Serrato-Recio, Antonio Jesús;Sánchez, Rosario;Pérez-Ruíz, Juan Manuel;Domínguez-Del Toro, Fernando:
PROGRAMMED CELL DEATH IN DEVELOPING AND GERMINATING CEREAL GRAINS. Current Topics in Plant Biology. 2002. Vol: 3. Núm: 1. Pág. 167-173.
PROGRAMMED CELL DEATH IN DEVELOPING AND GERMINATING CEREAL GRAINS. Current Topics in Plant Biology. 2002. Vol: 3. Núm: 1. Pág. 167-173.
