Directorio
MARIA ISABEL GARCIA MORENO
Categoría
Profesor Titular de Universidad
Departamento
Área
Química Orgánica
Docencia
Asignaturas que imparte
Investigación
Grupo de investigación
QUIMICA BIOORGANICA DE CARBOHIDRATOS (QUIMICA BIOORGANICA DE CARBOHI)
Proyectos y contratos de investigación
GLICOMIMÉTICOS MONO Y OLOGOSACARÍDICOS Y ESTUDIO DE SUS INTERACCIONES CON BIOMOLÉCULAS (CTQ2004-05854 - Investigador/a)
PREPARACIÓN, ANÁLISIS Y EVALUACIÓN DE OLIGOSACÁRIDOS PREBIÓTICOS DERIVADOS DE SACAROSA, FRUCTOSA Y LACTOSA (P06-AGR-02150 - Investigador/a)
GLICOBIÓTICOS Y GLICOFÁRMACOS: PREPARACIÓN Y EVALUACIÓN DE CARBOHIDRATOS CON ACTIVIDAD PROBIÓTICA (DAFS) Y BIOMÉDICA (GANGLOSIDOSIS GM1 Y ÁNTRAX) (CTQ2007-61180 - Investigador/a)
BLENDED-LEARNING CON WEB CT EN UNA ASIGNATURA EXPERIMENTAL DE LA LICENCIATURA DE QUÍMICA. EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA (891/2007 - Investigador/a)
SYNTHESIS AND BIOLOGICAL EVALUATION OF POLYVALENT GLYCOSIDASE INHIBITORS AS CHEMICAL CHAPERONS FOR THE TREATMENT OF LYSOSOMAL STORAGE DISORDERS (HU-2007-0006 - Investigador/a)
INNOVACIÓN DOCENTE EN EL LABORATORIO A TRAVÉS DEL DESARROLLO DE PROYECTOS. EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA (1571/2007 - Investigador/a)
DISEÑO DE INHIBIDORES DE GLICOSIDASAS PARA EL TRATAMIENTO DE ENFERMEDADES LISOSOMIALES: SINTESIS DE SP2-AZAAZUCARES Y EVALUACION EN TERAPIAS DE ACOMPA (P08-FQM-3711 - Responsable)
EL APRENDIZAJE EN GRUPOS COOPERATIVOS COMO FORMA DE TRABAJO PARA IMPLEMENTAR LA DOCENCIA INNOVADORA EN EL LABORATORIO BASADA EN EL DESARROLLO DE PROYE (XXXX - Investigador/a)
IMINOAZÚCARES SP2 COMO CHAPERONAS QUÍMICAS: UNA ESTRATEGIA GENERAL PARA EL TRATAMIENTO DE DESÓRDENES DE ALMACENAMIENTO LISOSOMIAL (FRA2009-001 - Investigador/a)
SISTEMA INTEGRADO DE TÉCNICAS ANALÍTICAS CG-MS/UV (UNSE08-1E-003 - Investigador/a)
GLICOBIÓTICOS, GLICOFÁRMACOS Y GLICOTRANSPORTADORES: APLICACIONES EN NUTRICIÓN Y BIOMEDICINA (SAF2010-15670 - Investigador/a)
CICLODEXTRINAS DENDRITICAS: APLICACION DEL CONCEPTO DE MULTIVALENCIA AL TRANSPORTE DE MEDICAMENTOS. (HF1999-0078 - Investigador/a)
SÍNTESIS Y EVALUACIÓN DE GLICOMIMÉTICOS COMO INHIBIDORES DE GLICOSIDASAS. APLICACIONES AL ESTUDIO DEL MODO DE ACCIÓN DE INVERTASAS Y SACAROSA SINTASA (BMC2001-2366-C03-03 - Investigador/a)
Ayudas para Actividades de Divulgación Científica (2019 III.3 - Investigador/a)
Programa al Estímulo de Áreas con Necesidades Investigadoras y de la Actividad Investigadora Emergente (VIIPPIT-2022-V.1 - Participante)
Solicitud de un cromatógrafo de gases de dos canales, ambos con detector FID para uso en cromatografía quiral (IE17/5850 - Investigador/a)
Adquisición de equipamiento destinado a control y estudios mecanísticos y cinéticos de reacciones orgánicas mediante técnicas espectroscópicas. (EQC2019-005433-P - Investigador/a)
Adquisición de un equipo de Cromatografía de fluidos Supercríticos (HPLC-SFC) (IE19_148 USE - Investigador/a)
Adquisición de un equipo de cromatografía de Gases con detectores FID y Masas y sistemas de cromatografía FLASH/LC complementados con un sistema de Cr (EQC2018-004416-P - Investigador/a)
Terapias Basadas en Glicomiméticos para el Tratamiento de Enfermedades de Plegamiento de Proteínas, Inflamación y Cáncer. (SAF2016-76083-R - Investigador/a)
Chaperonas, Inhibidores y Nutracéuticos Basados en Carbohidratos para Aplicaciones Biomédicas: Desórdenes de Depósito Lisosomal, Cáncer y Enfermedad d (SAF2013-44021-R - Investigador/a)
Adquisición de un equipo de cromatografía líquida de alta resolución y de sistemas para síntesis en continuo, en paralelo y a baja temperatura (UNSE15-CE-2892 - Investigador/a)
Terapias Basadas en Glicomiméticos para el tratamiento de Enfermedades de Plegamiento de Proteinas, Inflamación y Cancer (SAF2016-76083-R - Investigador/a)
Chaperonas, Inhibidores y Nutracéuticos Basados en Carbohidratos para Aplicaciones Biomédicas: Desórdenes de Depósito Lisosomal, Cáncer y Enfermedad d (SAF2013-44021-R - Investigador/a)
Incentivos al Grupo de Investigación FQM-308 (2011/FQM-308 - Investigador/a)
Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2006/FQM-308 - Investigador/a)
Synthesis and biological evalutation of polyvalent glycosidase inhibitors as chemical chaperones for the treatment of lysosomal disorders (HU2007-0006 - Investigador/a)
Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2007/FQM-308 - Investigador/a)
Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2008/FQM-308 - Investigador/a)
Incentivo al Grupo de Investigación FQM-308 (2010/FQM-308 - Investigador/a)
Puesta a punto de métodos eficaces para la transformación de productos derivados de las industrias azucarera y láctea en oligosacáridos prebióticos (OG-150/05 - Investigador/a)
Adquisición de nuevo equipamiento científico para laboratorios de investigación (UNSE10-1E-507 - Investigador/a)
Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2009/FQM-308 - Investigador/a)
Fabrication of particles with photo receptors: bio-analytical application such as controlled drug delivery (PIRSES-GA-2010-269099 - Investigador/a)
Libros publicados
Cabrera-Escribano, Francisca;Díez-Martín, Elena;Fernández-Fernández, Rosario;Fernandez-Bolaños-Guzman, Jose Maria;Garcia-Moreno, María Isabel;Lopez-Lopez, Oscar;Maya-Castilla, Ines;Moreno-Vargas, Antonio José:
EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA//EXPERIMENTAL ORGANIC SYNTHESIS. SECRETARIADO DE RECURSOS AUDIOVISUALES DE LA UNIVERSIDAD DE SEVILLA. 2010. 978-84-693-8370-4
EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA//EXPERIMENTAL ORGANIC SYNTHESIS. SECRETARIADO DE RECURSOS AUDIOVISUALES DE LA UNIVERSIDAD DE SEVILLA. 2010. 978-84-693-8370-4
Borrachero-Moya, Pastora;Maya-Castilla, Ines;Moreno-Vargas, Antonio José;Rodriguez-Carvajal, Miguel Angel;Tejero-Mateo, Pilar;Vázquez-Cabello, Juan;Fernández-Fernández, Rosario;Cabrera-Escribano, Francisca;Díez-Martín, Elena;Fernandez-Bolaños-Guzman, Jose Maria;Garcia-Moreno, María Isabel;Gil-Serrano, Antonio Miguel;Lopez-Lopez, Oscar;Martín-Zamora, María Eloísa:
EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA. UNIVERSIDAD DE SEVILLA. 2009. 978-84-692-5277-2
EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA. UNIVERSIDAD DE SEVILLA. 2009. 978-84-692-5277-2
Díez-Martín, Elena;Fernández-Fernández, Rosario;Garcia-Moreno, María Isabel;Maya-Castilla, Ines;Jimenez-Blanco, Jose Luis;Borrachero-Moya, Pastora;Tejero-Mateo, Pilar;Lopez-Lopez, Oscar;Martín-Zamora, María Eloísa;Vázquez-Cabello, Juan;Cabrera-Escribano, Francisca;Fernandez-Bolaños-Guzman, Jose Maria;Moreno-Vargas, Antonio José;Rodriguez-Carvajal, Miguel Angel;Gil-Serrano, Antonio Miguel:
EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA. UNIVERSIDAD DE SEVILLA. 2008. 978-84-691-1905-1
EXPERIMENTACIÓN EN SÍNTESIS ORGÁNICA. UNIVERSIDAD DE SEVILLA. 2008. 978-84-691-1905-1
Capítulos en Libros
Sanchez-Fernández, Elena Matilde;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen:
sp2-Iminosugars as chemical mimics for glycodrug design. Pág. 197-224. ELSEVIER. ELSEVIER. 2019.
sp2-Iminosugars as chemical mimics for glycodrug design. Pág. 197-224. ELSEVIER. ELSEVIER. 2019.
Asistencia a congresos
González, Manuel;Herrera-gonzález, Irene;Garcia-Moreno, María Isabel;Ashmus, Roger A;Vocadlo, David J. ;Garcia-Fernandez, Jose Manuel;Nanba, Eiji ;Higaki, Katsumi ;Ortiz Mellet, Carmen:
New candidates to adress late onset Tay-Sachs disease: sp2-iminosugar pharmacological chaperones. Poster en Congreso. XVIII Simposio de Jóvenes Investigadores Químicos. Centro de Investigaciones Científicas de la Isla de la Cartuja, Sevilla (España). 2022
New candidates to adress late onset Tay-Sachs disease: sp2-iminosugar pharmacological chaperones. Poster en Congreso. XVIII Simposio de Jóvenes Investigadores Químicos. Centro de Investigaciones Científicas de la Isla de la Cartuja, Sevilla (España). 2022
Medina Galera, Ángela ;Garcia-Moreno, María Isabel;Ortiz Mellet, Carmen:
Preparation of multivalent glycolipids with anti-inflammatory activity. Comunicación en congreso. I Congreso Sectorial de Estudiantes de Química. Sevilla. 2022
Preparation of multivalent glycolipids with anti-inflammatory activity. Comunicación en congreso. I Congreso Sectorial de Estudiantes de Química. Sevilla. 2022
Sanchez-Fernández, Elena Matilde;Masgrau, Laura;Ortiz Mellet, Carmen;Garcia-Moreno, María Isabel;Arroba, Ana Isabel;Aguilar-Diosdado, Manuel;Padrón, José Manuel;García-Hernández, Raquel;Gamarro-Conde, Francisco;Garcia-Fernandez, Jose Manuel;Sánchez-aparicio, José Enrique:
sp2-Iminosugar glycolipid mimetics as immunoregulatory agents. Comunicación en congreso. V Chemical Biology Group Meeting. Granada (España). 2020
sp2-Iminosugar glycolipid mimetics as immunoregulatory agents. Comunicación en congreso. V Chemical Biology Group Meeting. Granada (España). 2020
Garcia-Moreno, María Isabel;Sanchez-Fernández, Elena Matilde;Padrón, José Mamuel;García-Hernández, Raquel;Gamarro-Conde, Francisco;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen:
"Click" Synthesis and Pharmacological Evaluation of sp2-Iminosugars S- and C-Glycosides. Poster en Congreso. V Chemical Biology Group Meeting. Granada (España). 2020
"Click" Synthesis and Pharmacological Evaluation of sp2-Iminosugars S- and C-Glycosides. Poster en Congreso. V Chemical Biology Group Meeting. Granada (España). 2020
Sanchez-Fernández, Elena Matilde;Garcia-Moreno, María Isabel;Arroba, Ana Isabel;Padro¿n, Jose¿ Manuel;García-Hernández, Raquel;Gamarro-Conde, Francisco;Garcia-Fernandez, Jose Manuel;Masgrau, Laura;Ortiz Mellet, Carmen:
Polyfluoroalkyl Glycolipid Mimetics as Immunomodulatory Agents. Poster en Congreso. 20th European Carbohydrate Symposium. Leiden (Holanda). 2019
Polyfluoroalkyl Glycolipid Mimetics as Immunomodulatory Agents. Poster en Congreso. 20th European Carbohydrate Symposium. Leiden (Holanda). 2019
Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen;Suzuki, Yoshiyuki;Mena-Barragán, Teresa;Garcia-Moreno, María Isabel;Sevs¿ek, Alev;Okazaki, Tetsuya;Nanba, Eiji;Higaki, Katsumi;Martin, Nathaniel I.;Pieters, Roland J.:
Tailoring the inhibitory versus chaperoning behavior of amphiphilic sp2-iminosugar glycomimetics targeting ß-glucocerebrosidase: From micromolar to pi. Poster en Congreso. 15th WORLDSymposium. Orlando (EE.UU). 2019
Tailoring the inhibitory versus chaperoning behavior of amphiphilic sp2-iminosugar glycomimetics targeting ß-glucocerebrosidase: From micromolar to pi. Poster en Congreso. 15th WORLDSymposium. Orlando (EE.UU). 2019
Garcia-Moreno, María Isabel;Nierengarten, Jean-françois;Ortiz Mellet, Carmen;González, Manuel;Nierengarten, Iwona;González-cuesta, Manuel;Rodríguez-guerra, Jaime;Romero-tellez, Sonia;Maréchal, Jean-didier;Masgrau, Laura;Hahn, Uwe;Garcia-Fernandez, Jose Manuel:
Unravelling new binding modes in multivalent glycosidase inhibition with pillar[5]arene glyco(mimetic)rotaxanes. Comunicación en congreso. 29th International Carbohydrate Symposium. Lisboa (Portugal). 2018
Unravelling new binding modes in multivalent glycosidase inhibition with pillar[5]arene glyco(mimetic)rotaxanes. Comunicación en congreso. 29th International Carbohydrate Symposium. Lisboa (Portugal). 2018
Ortiz Mellet, Carmen;Garcia-Moreno, María Isabel;Ortega-Caballero, Fernando;Rísquez-Cuadro, Rocío;Garcia-Fernandez, Jose Manuel:
Heteromultivalency in lectin recognition and glycosidase inhibition. Poster en Congreso. 19th European Carbohydrate Symposium. Barcelona. 2017
Heteromultivalency in lectin recognition and glycosidase inhibition. Poster en Congreso. 19th European Carbohydrate Symposium. Barcelona. 2017
Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen;De La Mata-Fernández, Mario;Sanchez-Fernández, Elena Matilde;Díaz-Quintana, Antonio;Fustero, Santos;Nanba, Eiji;Higaki, Katsumi;Sánchez-Alcázar, José Antonio:
Undistortable fluorinated chaperone-beta-cyclodextrin formulations for neuronopathic Gaucher disease. Comunicación en congreso. 19th European Carbohydrate Symposium. Barcelona. 2017
Undistortable fluorinated chaperone-beta-cyclodextrin formulations for neuronopathic Gaucher disease. Comunicación en congreso. 19th European Carbohydrate Symposium. Barcelona. 2017
Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen;De La Mata-Fernández, Mario;Sanchez-Fernández, Elena Matilde;Benito-Hernandez, Juan Manuel;Díaz-Quintana, Antonio;Fustero, Santos;Nanba, Eiji;Higaki, Katsumi;Sánchez-Alcázar, José Antonio:
Undistortable fluorinated chaperone-beta-cyclodextrin formulations for neuronopathic Gaucher disease. Poster en Congreso. 19th European Carbohydrate Symposium. Barcelona. 2017
Undistortable fluorinated chaperone-beta-cyclodextrin formulations for neuronopathic Gaucher disease. Poster en Congreso. 19th European Carbohydrate Symposium. Barcelona. 2017
Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen;Sanchez-Fernández, Elena Matilde;De La Mata-Fernández, Mario;Garcia-Moreno, María Isabel;Benito-Hernandez, Juan Manuel;Nanba, Eiji;Suzuki, Yoshiyuki;Higaki, Katsumi;Sanchez-alcazar, Jose A.:
Fluorinated chaperone-beta-cyclodextrin formulations for neuronophatic Gaucher disease. Poster en Congreso. 13th Annual WORLDSymposium. San Diego, California (Estados Unidos). 2017
Fluorinated chaperone-beta-cyclodextrin formulations for neuronophatic Gaucher disease. Poster en Congreso. 13th Annual WORLDSymposium. San Diego, California (Estados Unidos). 2017
Garcia-Moreno, María Isabel;Mena-Barragán, Teresa;Concia, Alda Lisa;Nanba, Eiji;Higaki, Katsumi;Clapés, Pere;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen:
Chemoenzymatic Synthesis and Glycosidase Inhibitory Properties of New Piperidine, Pyrrolidine and Pyrrolizidine Derivatives. Poster en Congreso. 7th Spanish Portuguese Japanese Organic Chemistry Symposium . Sevilla (España). 2015
Chemoenzymatic Synthesis and Glycosidase Inhibitory Properties of New Piperidine, Pyrrolidine and Pyrrolizidine Derivatives. Poster en Congreso. 7th Spanish Portuguese Japanese Organic Chemistry Symposium . Sevilla (España). 2015
Alfonso-palacín, Mª Pilar;Giraldo-castellano, Pilar;Gervas-arruga, Javier;Andreu-gargallo, Vanesa;Garcia-Moreno, María Isabel;Mari-Beffa, Manuel;Urdiales-Ruiz, Jose Luis;Sánchez-Jiménez, Francisca Maria.;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
Study of the distribution of derivatives of L-idonojirimycin in nervous tissues. Poster en Congreso. 11th European Working Group on Gaucher Disease. Halifax (Israel). 2014
Study of the distribution of derivatives of L-idonojirimycin in nervous tissues. Poster en Congreso. 11th European Working Group on Gaucher Disease. Halifax (Israel). 2014
Ortiz Mellet, Carmen;Garcia-Moreno, María Isabel;Sanchez-Fernández, Elena Matilde;Garcia-Fernandez, Jose Manuel:
Glycosidase Inhibitors and Effectors as Therapeutic Tools. Conferencia Congreso no publicada. XI Jornadas de Carbohidratos. Logroño (España). 2014
Glycosidase Inhibitors and Effectors as Therapeutic Tools. Conferencia Congreso no publicada. XI Jornadas de Carbohidratos. Logroño (España). 2014
Garcia-Moreno, María Isabel;Higaki, Katsumi;Suzuki, Yoshiyuki;Garcia-Fernandez, Jose Manuel;Ortiz-Mellet, Carmen:
Development of a Pharmacological Chaperone Therapy for GM1-Gangliosidosis. Poster en Congreso. 2nd Meeting of the RSEQ Chemical Biology Group. Bilbao (España). 2014
Development of a Pharmacological Chaperone Therapy for GM1-Gangliosidosis. Poster en Congreso. 2nd Meeting of the RSEQ Chemical Biology Group. Bilbao (España). 2014
Gonçalves-pereira, Rita;Anjo, Carlos;Benito-Hernandez, Juan Manuel;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Figueiredo, J. Albertino;Ismael, M. Isabel;Ortiz Mellet, Carmen;Rauter, Amelia Pilar:
Carbohydrate-derived compounds as dual inhibitors for acetylcholinesterase and Aß aggregation . Poster en Congreso. 10º Encontro Nacional de Química Orgânica. Lisboa, Portugal. 2013
Carbohydrate-derived compounds as dual inhibitors for acetylcholinesterase and Aß aggregation . Poster en Congreso. 10º Encontro Nacional de Química Orgânica. Lisboa, Portugal. 2013
Ortiz Mellet, Carmen;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel:
sp2-Iminosugar glycosidase inhibitors: Synthetic strategies and therapeutic applications.. Conferencia Congreso no publicada. GECO 54, Groupe d'Etudes en Chimie Organique. Le Croisic, Francia. 2013
sp2-Iminosugar glycosidase inhibitors: Synthetic strategies and therapeutic applications.. Conferencia Congreso no publicada. GECO 54, Groupe d'Etudes en Chimie Organique. Le Croisic, Francia. 2013
Alfonso, Pilar ;Giraldo, Pilar;Andreu, Vanesa ;Pino-Ángeles, Almudena;Moya-García, Aurelio Ángel;Garcia-Moreno, María Isabel;Sánchez-Jiménez, Francisca Maria.;Pocovi, Miguel ;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease. Poster en Congreso. 18th Annual Congress of the European Hematology Association. Estocolmo, Suecia. 2013
Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease. Poster en Congreso. 18th Annual Congress of the European Hematology Association. Estocolmo, Suecia. 2013
Alfonso, Pilar;Giraldo, Pilar;Andreu, Vanesa;Pino-angeles, Almudena;Moya-garcia, Aurelio A.;Garcia-Moreno, María Isabel;Sánchez-jiménez, Francisca;Pocoví, Miguel;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
Use of the L-idonojirimycin derivatives as pharmacological chaperones for the treatment of Gaucher disease. Poster en Congreso. Lysosomal disease network's 9th annual Research Meeting. FLORIDA, ORLANDO (USA). 2013
Use of the L-idonojirimycin derivatives as pharmacological chaperones for the treatment of Gaucher disease. Poster en Congreso. Lysosomal disease network's 9th annual Research Meeting. FLORIDA, ORLANDO (USA). 2013
Alfonso, Pilar;Giraldo, Pilar;Andreu, Vanesa;Pino-angeles, Almudena;Moya-garcia, Aurelio A.;Garcia-Moreno, María Isabel;Sanchez-jimenez, Francisca;Pocoví, Miguel;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
Use of L-idonojirimycin derivatives as pharmacological chaperonoes for the treatment of Gaucher disease. Comunicación en congreso. VI Reunion Cientifica Anual CIBERER. San Lorenzo de El Escorial, Madrid. 2013
Use of L-idonojirimycin derivatives as pharmacological chaperonoes for the treatment of Gaucher disease. Comunicación en congreso. VI Reunion Cientifica Anual CIBERER. San Lorenzo de El Escorial, Madrid. 2013
Alfonso, Pilar;Garcia-Fernandez, Jose Manuel;Giraldo, Pilar;Andreu, Vanesa;Navascues, J;Pino-angeles, Almudena;Moya-garcia, Aurelio A.;Garcia-Moreno, María Isabel;Sanchez-jimenez, Francisca;Pocoví, Miguel;Ortiz-Mellet, Carmen:
Nuevos derivados bicíclicos de L-idonojirimicina como chaperonas farmacológicas para el tratamiento de la enfermedad de Gaucher. Comunicación en congreso. LIV Reunión Anual de la Sociedad Española de Hematología y Hemoterapia. . 2012
Nuevos derivados bicíclicos de L-idonojirimicina como chaperonas farmacológicas para el tratamiento de la enfermedad de Gaucher. Comunicación en congreso. LIV Reunión Anual de la Sociedad Española de Hematología y Hemoterapia. . 2012
Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Aguilar-Moncayo, Matilde;Mena-Barragán, Teresa;Takai, Tomoko;Li, Linjing;Higaki, Katsumi;Ohno, Kousaku;Suzuki, Yoshiyuki;Ortiz-Mellet, Carmen:
ANOMERIC SELECTIVE PHARMACOLOGICAL CHAPERONES FOR LSDs BASED ON NON-GLYCONIC INTERACTIONS. Comunicación en congreso. 26th International Carbohydrate Symposium. MADRID (ESPAÑA). 2012
ANOMERIC SELECTIVE PHARMACOLOGICAL CHAPERONES FOR LSDs BASED ON NON-GLYCONIC INTERACTIONS. Comunicación en congreso. 26th International Carbohydrate Symposium. MADRID (ESPAÑA). 2012
Alfonso, P;Garcia-Fernandez, Jose Manuel;Giraldo, P;Andreu, V;Navascues, J;Pino-angeles, A;Moya-garcía, A A;Garcia-Moreno, María Isabel;Sánchez-jiménez, F;Pocoví, M;Ortiz-Mellet, Carmen:
EXPLORING BICYCLIC DERIVATIVES OF L-IDONOJIRIMYCIN AS PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF GAUCHER DISEASE. Poster en Congreso. 10th EUROPEAN WORKING GROUP ON GAUCHER DISEASE. PARIS, FRANCIA. 2012
EXPLORING BICYCLIC DERIVATIVES OF L-IDONOJIRIMYCIN AS PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF GAUCHER DISEASE. Poster en Congreso. 10th EUROPEAN WORKING GROUP ON GAUCHER DISEASE. PARIS, FRANCIA. 2012
Aguilar-Moncayo, Matilde;Garcia-Fernandez, Jose Manuel;Mena-Barragán, Teresa;Garcia-Moreno, María Isabel;Takai, Tomoko;Linjing, Li;Higaki, Katsumi;Ohno, Kousaku;Yoshiyuki, Suzuki;Ortiz-Mellet, Carmen:
RATIONAL DESIGN OF PHARMACOLOGICAL CHAPERONES FOR LYSOSOMAL STORAGE DISORDERS. Poster en Congreso. First Biennial Meeting Chemical Biology Group . Santiago de Compostela, Spain. 2012
RATIONAL DESIGN OF PHARMACOLOGICAL CHAPERONES FOR LYSOSOMAL STORAGE DISORDERS. Poster en Congreso. First Biennial Meeting Chemical Biology Group . Santiago de Compostela, Spain. 2012
Mena-Barragán, Teresa;Li-,Linjing;Garcia-Fernandez, Jose Manuel;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Luan-,Z;Namba-,E;Ohno-,K;Ortiz-Mellet, Carmen;Higaki-,K;Suzuki-,Yasuhiro:
sp2-IMINOSUGAR-TYPE (GALACTO)NOJIRIMYCIN ANALOGUES WITH PHARMACOLOGICAL CHAPERONE ACTIVITY FOR GM1-GANGLIOSIDOSIS AND FABRY DISEASE. Poster en Congreso. 16 th European Carbohydrate Symposium. SORRENTO, ITALIA. 2011
sp2-IMINOSUGAR-TYPE (GALACTO)NOJIRIMYCIN ANALOGUES WITH PHARMACOLOGICAL CHAPERONE ACTIVITY FOR GM1-GANGLIOSIDOSIS AND FABRY DISEASE. Poster en Congreso. 16 th European Carbohydrate Symposium. SORRENTO, ITALIA. 2011
Mena-Barragán, Teresa;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND COMPARATIVE GLYCOSIDASE INHIBITORY PROPERTIES OF 1-DEOXY-SP2-IMINOSUGARS. Poster en Congreso. X Jornadas de Carbohidratos. GRANADA. 2010
SYNTHESIS AND COMPARATIVE GLYCOSIDASE INHIBITORY PROPERTIES OF 1-DEOXY-SP2-IMINOSUGARS. Poster en Congreso. X Jornadas de Carbohidratos. GRANADA. 2010
Rísquez-Cuadro, Rocío;Sanchez-Fernández, Elena Matilde;Ortiz-Mellet, Carmen;Garcia-Moreno, María Isabel;Ouadid-Ahidouch-,Halima;Garcia-Fernandez, Jose Manuel:
STEREOSELECTIVE SYNTHESIS OF N-, S- AND C-GLYCOSIDE CASTANOSPERMINE ANALOGUES AS ANTITUMOR AGENTS. Comunicación en congreso. X Jornadas de Carbohidratos. GRANADA. 2010
STEREOSELECTIVE SYNTHESIS OF N-, S- AND C-GLYCOSIDE CASTANOSPERMINE ANALOGUES AS ANTITUMOR AGENTS. Comunicación en congreso. X Jornadas de Carbohidratos. GRANADA. 2010
Ortiz-Mellet, Carmen;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Luan-,Z;Ohno-,K;Higaki-,K;Garcia-Fernandez, Jose Manuel;Suzuki-,Yasuhiro:
SYNTHESIS OF BICYCLIC SP2-IMINOSUGARS AND EVALUATION OF THEIR CHAPERONE ACTIVITY FOR GAUCHER AND GM1-GANGLIOSIDOSIS MUTATIONS. Poster en Congreso. 25th International Carbohydrate Symposium. CHIBA, JAPON. 2010
SYNTHESIS OF BICYCLIC SP2-IMINOSUGARS AND EVALUATION OF THEIR CHAPERONE ACTIVITY FOR GAUCHER AND GM1-GANGLIOSIDOSIS MUTATIONS. Poster en Congreso. 25th International Carbohydrate Symposium. CHIBA, JAPON. 2010
Luan, Zhuo;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Higaki, Katsumi;Aguilar-Moncayo, Matilde;Li, Linjing;Ninomiya, Haruaki;Nanba, Eiji;Ohno, Kousaku;Garcia-Moreno, María Isabel;Suzuki, Yoshiyuki:
SP2-IMINOSUGARS AS PHARMACOLOGICAL CHAPERONES FOR GAUCHER DISEASE: MUTATION PROFILING, CELLULAR UPTAKE AND INTRACELLULAR DISTRIBUTION STUDIES. Poster en Congreso. 9th International European Working Group on Gaucher Disease. COLOGNE, ALEMANIA. 2010
SP2-IMINOSUGARS AS PHARMACOLOGICAL CHAPERONES FOR GAUCHER DISEASE: MUTATION PROFILING, CELLULAR UPTAKE AND INTRACELLULAR DISTRIBUTION STUDIES. Poster en Congreso. 9th International European Working Group on Gaucher Disease. COLOGNE, ALEMANIA. 2010
Ortiz-Mellet, Carmen;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel:
SP2-IMINOSUGARS AS CHEMICAL CHAPERONES: TACKLING ENZYME SELECTIVITY THROUGH GLYCOMIMETIC DESIGN. Conferencia Congreso no publicada. XXIIIÈMES JOURNÉES DU GROUPE FRANÇAIS DES GLUCIDES. SAINT- VALERYSUR-SOMME, FRANCIA. 2010
SP2-IMINOSUGARS AS CHEMICAL CHAPERONES: TACKLING ENZYME SELECTIVITY THROUGH GLYCOMIMETIC DESIGN. Conferencia Congreso no publicada. XXIIIÈMES JOURNÉES DU GROUPE FRANÇAIS DES GLUCIDES. SAINT- VALERYSUR-SOMME, FRANCIA. 2010
Aguilar-Moncayo, Matilde;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Garcia-Moreno, María Isabel:
SINTESIS DE ANALOGOS DE CASTANOSPERMINA Y SU INTERACCION CON ENZIMAS LISOSOMALES. Comunicación en congreso. 23 Reunión Bienal de Química Orgánica. MURCIA. 2010
SINTESIS DE ANALOGOS DE CASTANOSPERMINA Y SU INTERACCION CON ENZIMAS LISOSOMALES. Comunicación en congreso. 23 Reunión Bienal de Química Orgánica. MURCIA. 2010
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Wrodnigg, Tanja M;Stütz, Arnold E;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
FLUORESCENT-TAGGED SP2-IMINOSUGARS WITH POTENT BETA-GLUCOSIDASE INHIBITORY ACTIVITY. Poster en Congreso. 15 th European Carbohydrate Symposium. VIENA, AUSTRIA. 2009
FLUORESCENT-TAGGED SP2-IMINOSUGARS WITH POTENT BETA-GLUCOSIDASE INHIBITORY ACTIVITY. Poster en Congreso. 15 th European Carbohydrate Symposium. VIENA, AUSTRIA. 2009
Ortiz-Mellet, Carmen;Sanchez-Fernández, Elena Matilde;Rísquez-Cuadro, Rocío;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel:
N-, S-, C- AND O-GLYCOSIDE CASTANOSPERMINE ANALOGUES: AGLYCON-SENSITIVE GLYCOSIDASE INHIBITORS. Poster en Congreso. 15 th European Carbohydrate Symposium. VIENA, AUSTRIA. 2009
N-, S-, C- AND O-GLYCOSIDE CASTANOSPERMINE ANALOGUES: AGLYCON-SENSITIVE GLYCOSIDASE INHIBITORS. Poster en Congreso. 15 th European Carbohydrate Symposium. VIENA, AUSTRIA. 2009
Garcia-Fernandez, Jose Manuel;Ortiz-Mellet, Carmen;Garcia-Moreno, María Isabel:
NEW APPROACHES TO GLYCOSIDASE INHIBITION: SYNTHESIS AND THERAPEUTIC POTENTIAL OF SP2-IMINOSUGARS. Conferencia Congreso no publicada. 15 th European Carbohydrate Symposium. VIENA, AUSTRIA. 2009
NEW APPROACHES TO GLYCOSIDASE INHIBITION: SYNTHESIS AND THERAPEUTIC POTENTIAL OF SP2-IMINOSUGARS. Conferencia Congreso no publicada. 15 th European Carbohydrate Symposium. VIENA, AUSTRIA. 2009
Garcia-Moreno, María Isabel;Aguilar-Moncayo, Matilde;Sanchez-Fernández, Elena Matilde;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
RING-MODIFIED CASTANOSPERMINES AS GLYCOSIDASE INHIBITORS: ENZYMESELECTIVITY VS INHIBITION POTENCY. Poster en Congreso. IV Iberian Carbohydrate Meeting. SANTIAGO DE COMPOSTELA. 2008
RING-MODIFIED CASTANOSPERMINES AS GLYCOSIDASE INHIBITORS: ENZYMESELECTIVITY VS INHIBITION POTENCY. Poster en Congreso. IV Iberian Carbohydrate Meeting. SANTIAGO DE COMPOSTELA. 2008
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Gloster-,Tracey M.;Davies-,Gideon J;Garcia-Fernandez, Jose Manuel:
KINETIC, THERMODYNAMIC AND STRUCTURAL ANALYSIS OF BETA-GLUCOSIDASE INHIBITION BY SP2 AZASUGARS. Comunicación en congreso. IV Iberian Carbohydrate Meeting. SANTIAGO DE COMPOSTELA. 2008
KINETIC, THERMODYNAMIC AND STRUCTURAL ANALYSIS OF BETA-GLUCOSIDASE INHIBITION BY SP2 AZASUGARS. Comunicación en congreso. IV Iberian Carbohydrate Meeting. SANTIAGO DE COMPOSTELA. 2008
Garcia-Moreno, María Isabel;Aguilar-Moncayo, Matilde;Ortiz-Mellet, Carmen;Benltifa-,Mahmoud;Wadouachi-,Anne;Garcia-Fernandez, Jose Manuel:
INTRODUCING MOLECULAR DIVERSITY IN THE CASTANOSPERMINE SKELETON. Poster en Congreso. 24th International Carbohydrate Symposium. OSLO, NORUEGA. 2008
INTRODUCING MOLECULAR DIVERSITY IN THE CASTANOSPERMINE SKELETON. Poster en Congreso. 24th International Carbohydrate Symposium. OSLO, NORUEGA. 2008
Ortiz-Mellet, Carmen;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Gloster-,Tracey M.;Davies-,Gideon J:
MOLECULAR BASIS FOR BETA-GLUCOSIDASE INHIBITION BY SP2-AZASUGARS OF THE NOR-TROPANE AND INDOLIZIDINE FAMILIES. Poster en Congreso. 24th International Carbohydrate Symposium. OSLO, NORUEGA. 2008
MOLECULAR BASIS FOR BETA-GLUCOSIDASE INHIBITION BY SP2-AZASUGARS OF THE NOR-TROPANE AND INDOLIZIDINE FAMILIES. Poster en Congreso. 24th International Carbohydrate Symposium. OSLO, NORUEGA. 2008
Sanchez-Fernández, Elena Matilde;Garcia-Moreno, María Isabel;Aguilar-Moncayo, Matilde;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
NUEVAS ESTRATEGIAS PARA LA INTRODUCCION DE DIVERSIDAD MOLECULAR EN EL ESQUELETO DE CASTANOSPERMINA. ESTUDIOS DE ESTRUCTURA-ACTIVIDAD. Comunicación en congreso. XXII Reunión Bienal de Química Orgánica. TARRAGONA, ESPAÑA. 2008
NUEVAS ESTRATEGIAS PARA LA INTRODUCCION DE DIVERSIDAD MOLECULAR EN EL ESQUELETO DE CASTANOSPERMINA. ESTUDIOS DE ESTRUCTURA-ACTIVIDAD. Comunicación en congreso. XXII Reunión Bienal de Química Orgánica. TARRAGONA, ESPAÑA. 2008
Benltifa-,Mahmoud;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;García-Fernández, José Manuel;Wadouachi-,Anne:
SYNTHESE ET EVALUATION DE L'ACTIVITE INHIBITRICE D'INDOLIZIDINES A MOTIFS SULFAMIDES. Comunicación en congreso. XXIIÈMES JOURNÉES DU GROUPE FRANCAIS DES GLUCIDES . BONASCRE, AX-LES-THERMES (FRANCIA). 2008
SYNTHESE ET EVALUATION DE L'ACTIVITE INHIBITRICE D'INDOLIZIDINES A MOTIFS SULFAMIDES. Comunicación en congreso. XXIIÈMES JOURNÉES DU GROUPE FRANCAIS DES GLUCIDES . BONASCRE, AX-LES-THERMES (FRANCIA). 2008
Garcia-Moreno, María Isabel;Aguilar-Moncayo, Matilde;Díaz-Pérez, Paula;Wadouachi-,Anne;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SÍNTESIS Y EVALUACIÓN BIOLÓGICA DE NUEVOS INHIBIDORES DE GLICOSIDASAS DE TIPO SP2-AZAAZÚCAR. Comunicación en congreso. XXXI Reunión Bienal de la Real Sociedad Española de Química. TOLEDO. 2007
SÍNTESIS Y EVALUACIÓN BIOLÓGICA DE NUEVOS INHIBIDORES DE GLICOSIDASAS DE TIPO SP2-AZAAZÚCAR. Comunicación en congreso. XXXI Reunión Bienal de la Real Sociedad Española de Química. TOLEDO. 2007
Garcia-Moreno, María Isabel;Aguilar-Moncayo, Matilde;Ortiz-Mellet, Carmen;Iwasaki-,H;Ohno-,K;Suzuki-,Yasuhiro;Garcia-Fernandez, Jose Manuel:
INHIBIDORES DE GLICOSIDASAS DE TIPO SP2-AZAAZÚCAR COMO ACOMPAÑANTES QUÍMICOS PARA EL TRATAMIENTO DE ENFERMEDADES LISOSOMIALES. Poster en Congreso. XXXI Reunión Bienal de la Real Sociedad Española de Química. TOLEDO. 2007
INHIBIDORES DE GLICOSIDASAS DE TIPO SP2-AZAAZÚCAR COMO ACOMPAÑANTES QUÍMICOS PARA EL TRATAMIENTO DE ENFERMEDADES LISOSOMIALES. Poster en Congreso. XXXI Reunión Bienal de la Real Sociedad Española de Química. TOLEDO. 2007
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Iwasaki-,H;Ohno-,K;Suzuki-,Yasuhiro;Garcia-Fernandez, Jose Manuel:
SP2-AZASUGAR GLYCOSIDASE INHIBITORS AS CHEMICAL CHAPERONS FOR THE TREATMENT OF LYSOSOMAL STORAGE DISORDERS. Poster en Congreso. Advances in Synthetic and Medicinal Chemistry. SAN PETERSBURGO, RUSIA. 2007
SP2-AZASUGAR GLYCOSIDASE INHIBITORS AS CHEMICAL CHAPERONS FOR THE TREATMENT OF LYSOSOMAL STORAGE DISORDERS. Poster en Congreso. Advances in Synthetic and Medicinal Chemistry. SAN PETERSBURGO, RUSIA. 2007
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND COMPARATIVE INHIBITORY PROPERTIES OF ISO(THIO)UREA-TYPE CASTANOSPERMINE ANALOGUES. Poster en Congreso. VIII Jornadas de Carbonhidratos. ALCALÁ DE HENARES, MADRID. 2006
SYNTHESIS AND COMPARATIVE INHIBITORY PROPERTIES OF ISO(THIO)UREA-TYPE CASTANOSPERMINE ANALOGUES. Poster en Congreso. VIII Jornadas de Carbonhidratos. ALCALÁ DE HENARES, MADRID. 2006
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
GUANIDINE-TYPE GLYCOMIMETICS RELATED TO THE POLYHYDROXYLATED PIPERIDINE AND INDOLIZIDINE ALKALOIDS. Poster en Congreso. VIII Jornadas de Carbonhidratos. ALCALÁ DE HENARES, MADRID. 2006
GUANIDINE-TYPE GLYCOMIMETICS RELATED TO THE POLYHYDROXYLATED PIPERIDINE AND INDOLIZIDINE ALKALOIDS. Poster en Congreso. VIII Jornadas de Carbonhidratos. ALCALÁ DE HENARES, MADRID. 2006
Garcia-Moreno, María Isabel;Mallet-,Jean-Maurice:
FIRST SUGAR LINKED CYCLODEXTRIN DUPLEX. TOWARD "SUPER CYCLODEXTRINS". Comunicación en congreso. XIII International Cyclodextrin Symposium. TORINO, ITALIA. 2006
FIRST SUGAR LINKED CYCLODEXTRIN DUPLEX. TOWARD "SUPER CYCLODEXTRINS". Comunicación en congreso. XIII International Cyclodextrin Symposium. TORINO, ITALIA. 2006
Louis-,Farida;Balbuena-Oliva, Patricia;Rubio-Castillo, Enrique Miguel;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
RIGID-SPACER MEDIATED SYNTHESIS OF SPIRO DISACCHARIDES. Poster en Congreso. 13TH EUROPEAN CARBOHYDRATE SYMPOSIUM. BRATISLAVA, ESLOVAQUIA. 2005
RIGID-SPACER MEDIATED SYNTHESIS OF SPIRO DISACCHARIDES. Poster en Congreso. 13TH EUROPEAN CARBOHYDRATE SYMPOSIUM. BRATISLAVA, ESLOVAQUIA. 2005
Balbuena-Oliva, Patricia;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Jimenez-Blanco, Jose Luis;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
THE O-XYLYLENE PROTECTING GROUP IN CARBOHYDRATE CHEMISTRY. Comunicación en congreso. 13TH EUROPEAN CARBOHYDRATE SYMPOSIUM. BRATISLAVA, ESLOVAQUIA. 2005
THE O-XYLYLENE PROTECTING GROUP IN CARBOHYDRATE CHEMISTRY. Comunicación en congreso. 13TH EUROPEAN CARBOHYDRATE SYMPOSIUM. BRATISLAVA, ESLOVAQUIA. 2005
Balbuena-Oliva, Patricia;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Jimenez-Blanco, Jose Luis;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
THE O-XYLYLENE PROTECTING GROUP IN CARBOHYDRATE CHEMISTRY. Poster en Congreso. 3RD IBERIAN CARBOHYDRATE MEETING (3) (3.2005.COIMBRA PORTUGAL). COIMBRA PORTUGAL. 2005
THE O-XYLYLENE PROTECTING GROUP IN CARBOHYDRATE CHEMISTRY. Poster en Congreso. 3RD IBERIAN CARBOHYDRATE MEETING (3) (3.2005.COIMBRA PORTUGAL). COIMBRA PORTUGAL. 2005
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Díaz-Moscoso, Alejandro;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
INDOLIZIDINE-TREHAZOLINE HYBRID GLYCOMIMETICS: NANOMOLAR INHIBITORS OF BETA-GALACTOSIDASES. Poster en Congreso. EUROPEAN CARBOHYDRATE SYMPOSIUM (13.2005.BRATISLAVA (ESLOVAQUIA)). BRATISLAVA (ESLOVAQUIA). 2005
INDOLIZIDINE-TREHAZOLINE HYBRID GLYCOMIMETICS: NANOMOLAR INHIBITORS OF BETA-GALACTOSIDASES. Poster en Congreso. EUROPEAN CARBOHYDRATE SYMPOSIUM (13.2005.BRATISLAVA (ESLOVAQUIA)). BRATISLAVA (ESLOVAQUIA). 2005
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Díaz-Moscoso, Alejandro;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
ISOUREA-TYPE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. Poster en Congreso. 3RD IBERIAN CARBOHYDRATE MEETING (3) (3.2005.COIMBRA PORTUGAL). COIMBRA PORTUGAL. 2005
ISOUREA-TYPE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. Poster en Congreso. 3RD IBERIAN CARBOHYDRATE MEETING (3) (3.2005.COIMBRA PORTUGAL). COIMBRA PORTUGAL. 2005
Rubio-Castillo, Enrique Miguel;Balbuena-Oliva, Patricia;Garcia-Moreno, María Isabel;Ortiz-Sáez,Carlos;Benito-Hernandez, Juan Manuel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
ESPIROOLIGOSACÁRIDOS:DE LA GASTRONOMÍA A LA QUÍMICA MOLECULAR. Conferencia Congreso no publicada. VII JORNADAS DE CARBOHIDRATOS. REUNIÓN DEL GRUPO CARBOHIDRATOS RSEQ . TARRAGONA. 2004
ESPIROOLIGOSACÁRIDOS:DE LA GASTRONOMÍA A LA QUÍMICA MOLECULAR. Conferencia Congreso no publicada. VII JORNADAS DE CARBOHIDRATOS. REUNIÓN DEL GRUPO CARBOHIDRATOS RSEQ . TARRAGONA. 2004
Ortiz-Mellet, Carmen;Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Garcia-Fernandez, Jose Manuel:
SÍNTESIS DE ANÁLOGOS DE INDOLIZIDINAS Y PIRROLIZIDINAS Y EVALUACIÓN BIOLÓGICA COMO INHIBIDORES DE GLICOSIDASAS. Poster en Congreso. VII JORNADAS DE CARBOHIDRATOS. REUNIÓN DEL GRUPO CARBOHIDRATOS RSEQ . TARRAGONA. 2004
SÍNTESIS DE ANÁLOGOS DE INDOLIZIDINAS Y PIRROLIZIDINAS Y EVALUACIÓN BIOLÓGICA COMO INHIBIDORES DE GLICOSIDASAS. Poster en Congreso. VII JORNADAS DE CARBOHIDRATOS. REUNIÓN DEL GRUPO CARBOHIDRATOS RSEQ . TARRAGONA. 2004
Rubio-Castillo, Enrique Miguel;Balbuena-Oliva, Patricia;Garcia-Moreno, María Isabel;Jimenez-Blanco, Jose Luis;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
EL GRUPO PROTECTOR XILENILENO EN QUÍMICA DE CARBOHIDRATOS:APLICACIONES AL CONTROL ESTEROQUÍMICO EN SÍNTESIS OLIGOSACARÍDICA. Poster en Congreso. VII JORNADAS DE CARBOHIDRATOS. REUNIÓN DEL GRUPO CARBOHIDRATOS RSEQ . TARRAGONA. 2004
EL GRUPO PROTECTOR XILENILENO EN QUÍMICA DE CARBOHIDRATOS:APLICACIONES AL CONTROL ESTEROQUÍMICO EN SÍNTESIS OLIGOSACARÍDICA. Poster en Congreso. VII JORNADAS DE CARBOHIDRATOS. REUNIÓN DEL GRUPO CARBOHIDRATOS RSEQ . TARRAGONA. 2004
Rubio-Castillo, Enrique Miguel;Balbuena-Oliva, Patricia;Benito-Hernandez, Juan Manuel;Garcia-Moreno, María Isabel;Ortiz-Sáez,Carlos;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SPIRO-OLIGOSACCHARIDES: NEW STRATEGIES FOR THE STEREOSELECTIVE SYNTHESIS OF DI-D-FRUCTOSE DIANHYDRIDES AND CYCLOFRUCTINS. Poster en Congreso. INTERNATIONAL CARBOHYDRATE SYMPOSIUM (22) (22.2004.GLASGOW). GLASGOW. 2004
SPIRO-OLIGOSACCHARIDES: NEW STRATEGIES FOR THE STEREOSELECTIVE SYNTHESIS OF DI-D-FRUCTOSE DIANHYDRIDES AND CYCLOFRUCTINS. Poster en Congreso. INTERNATIONAL CARBOHYDRATE SYMPOSIUM (22) (22.2004.GLASGOW). GLASGOW. 2004
Rubio-Castillo, Enrique Miguel;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SPIROKETALIC DISACCHARIDES: STEREOSELECTIVEW SYNTHESIS OF DI-D-FRUCTOSE DIANHYDRIDES VIA INTRAMOLECULAR AGLYCON DELIVERY. Poster en Congreso. 5TH INTERNATIONAL MEETING OF THE PORTUGUESE CARBOHYDRATE GROUP. COVILHA, PORTUGAL. 2003
SPIROKETALIC DISACCHARIDES: STEREOSELECTIVEW SYNTHESIS OF DI-D-FRUCTOSE DIANHYDRIDES VIA INTRAMOLECULAR AGLYCON DELIVERY. Poster en Congreso. 5TH INTERNATIONAL MEETING OF THE PORTUGUESE CARBOHYDRATE GROUP. COVILHA, PORTUGAL. 2003
Díaz-Pérez, Paula;Garcia-Moreno, María Isabel;Balbuena-Oliva, Patricia;Diaz-Perez,Vm;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SP2-AZASUGARS, AN EMERGING FAMILY OF HIGHLY SPECIFIC GLYCOSIDASE INHIBITORS. Comunicación en congreso. 12TH EUROPENA CARBOHYDRATE SYMPOSIUM. . 2003
SP2-AZASUGARS, AN EMERGING FAMILY OF HIGHLY SPECIFIC GLYCOSIDASE INHIBITORS. Comunicación en congreso. 12TH EUROPENA CARBOHYDRATE SYMPOSIUM. . 2003
Díaz-Pérez, Paula;Garcia-Moreno, María Isabel;Balbuena-Oliva, Patricia;Díaz-Pérez, Víctor;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SÍNTESIS DE ANÁLOGOS DE INDOLIZIDINAS Y PIRROLIZIDINAS Y EVALUACIÓN BIOLÓGICA COMO INHIBIDORES DE GLICOSIDASAS. Poster en Congreso. CENTENARIO DE LAS REALES SOCIEDADES DE FÍSICA Y QUÍMICA. XXIX REUNIÓN BIENAL DE LA RSEQ. . 2003
SÍNTESIS DE ANÁLOGOS DE INDOLIZIDINAS Y PIRROLIZIDINAS Y EVALUACIÓN BIOLÓGICA COMO INHIBIDORES DE GLICOSIDASAS. Poster en Congreso. CENTENARIO DE LAS REALES SOCIEDADES DE FÍSICA Y QUÍMICA. XXIX REUNIÓN BIENAL DE LA RSEQ. . 2003
Garcia-Moreno, María Isabel;Benito-Hernandez, Juan Manuel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
AZAAZÚCARES SP2, UNA NUEVA FAMILIA DE INHIBIDORES DE GLICOSIDASAS ALTAMENTE ESPECÍFICOS: SÍNTESIS Y EVALUACIÓN BIOLÓGICA DE ANÁLOGOS DE CALISTEGINAS. Poster en Congreso. CENTENARIO DE LAS REALES SOCIEDADES DE FÍSICA Y QUÍMICA. XXIX REUNIÓN BIENAL DE LA RSEQ. . 2003
AZAAZÚCARES SP2, UNA NUEVA FAMILIA DE INHIBIDORES DE GLICOSIDASAS ALTAMENTE ESPECÍFICOS: SÍNTESIS Y EVALUACIÓN BIOLÓGICA DE ANÁLOGOS DE CALISTEGINAS. Poster en Congreso. CENTENARIO DE LAS REALES SOCIEDADES DE FÍSICA Y QUÍMICA. XXIX REUNIÓN BIENAL DE LA RSEQ. . 2003
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND EVALUATION OF CALYSTEGINE ANALOGUES AND CASTANOSPERMINE-TREHAZOLIN HYBRIDS AS GLYCOSIDASE INHIBITORS. Comunicación en congreso. II IBERIAN CARBOHYDRATE MEETING. RONDA (ESPAÑA). 2002
SYNTHESIS AND EVALUATION OF CALYSTEGINE ANALOGUES AND CASTANOSPERMINE-TREHAZOLIN HYBRIDS AS GLYCOSIDASE INHIBITORS. Comunicación en congreso. II IBERIAN CARBOHYDRATE MEETING. RONDA (ESPAÑA). 2002
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND EVALUATION OF CASTANOSPERMINE, SWAINSONINE AND CALYSTEGINE B2 ANALOGS AS GLYCOSIDASE INHIBITORS. Comunicación en congreso. 11TH EUROPEAN CARBOHYDRATE SYMPOSIUM. LISBOA, PORTUGAL. 2001
SYNTHESIS AND EVALUATION OF CASTANOSPERMINE, SWAINSONINE AND CALYSTEGINE B2 ANALOGS AS GLYCOSIDASE INHIBITORS. Comunicación en congreso. 11TH EUROPEAN CARBOHYDRATE SYMPOSIUM. LISBOA, PORTUGAL. 2001
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Cañada-,F. Javier;Díaz-Arribas,Juan Carlos;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND GLYCOSIDASE INHIBITORY ACTIVITY OF RING-MODIFIED CALYSTEGINE ANALOGS. Poster en Congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
SYNTHESIS AND GLYCOSIDASE INHIBITORY ACTIVITY OF RING-MODIFIED CALYSTEGINE ANALOGS. Poster en Congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Cañada-, Javier;Díaz-Arribas,Juan Carlos;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND EVALUATION OF RING-MODIFIED CALYSTEGINE ANALOGS AS GLYCOSIDASE INHIBITORS. Comunicación en congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
SYNTHESIS AND EVALUATION OF RING-MODIFIED CALYSTEGINE ANALOGS AS GLYCOSIDASE INHIBITORS. Comunicación en congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
Benito-Hernandez, Juan Manuel;Garcia-Moreno, María Isabel;Diaz-Perez,Vm;Ortiz-Mellet, Carmen;Cañada-,F. Javier;Garcia-Fernandez, Jose Manuel;Díaz-Pérez, Paula:
N-(TIO) CARBONIL AZAAZUCARES: INHIBIDORES DE GLICOSIDASAS SENSIBLES A LA ANOMERIA. Ponencia en Congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
N-(TIO) CARBONIL AZAAZUCARES: INHIBIDORES DE GLICOSIDASAS SENSIBLES A LA ANOMERIA. Ponencia en Congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
Díaz-Pérez, Víctor;Benito-Hernandez, Juan Manuel;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Fuentes-Mota, Jose;Garcia-Fernandez, Jose Manuel:
SYNTHESIS, STEREOLECTRONIC PROPERTIES AND REATIVITY OF N-(THIO)CARBONIYLIMINOSUGARS. Poster en Congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
SYNTHESIS, STEREOLECTRONIC PROPERTIES AND REATIVITY OF N-(THIO)CARBONIYLIMINOSUGARS. Poster en Congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Cañada-,J.;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND GLYCOSIDASE INHIBITORY ACTIVITY OF RING-MODIFIED CALYSTEGINE ANALOGS. Comunicación en congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
SYNTHESIS AND GLYCOSIDASE INHIBITORY ACTIVITY OF RING-MODIFIED CALYSTEGINE ANALOGS. Comunicación en congreso. 10TH EUROPEAN CARBOHYDRATE SYMPOSIUM. GALWAY, IRLANDA. 1999
Díaz-Pérez, Víctor;Benito-Hernandez, Juan Manuel;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Fuentes-Mota, Jose;Garcia-Fernandez, Jose Manuel:
SÍNTESIS, PROPIEDADES ESTEREOELECTRÓNICAS Y REACTIVIDAD DE N-(TIO)CARBONILIMINOAZÚCARES. Comunicación en congreso. XVII REUNIÓN BIENAL DE QUÍMICA ORGÁNICA. LOGROÑO, ESPAÑA. 1998
SÍNTESIS, PROPIEDADES ESTEREOELECTRÓNICAS Y REACTIVIDAD DE N-(TIO)CARBONILIMINOAZÚCARES. Comunicación en congreso. XVII REUNIÓN BIENAL DE QUÍMICA ORGÁNICA. LOGROÑO, ESPAÑA. 1998
Rodríguez- Lavado, Julio;Jimenez-Blanco, Jose Luis;Garcia-Moreno, María Isabel;Benito-Hernandez, Juan Manuel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
DESIGN OF A GLYCOTARGETED CARRIER FOR RECEPTOR-MEDIATED DELIVERY OF PHARMACOLOGICAL CHAPERONES. Comunicación en congreso. . .
DESIGN OF A GLYCOTARGETED CARRIER FOR RECEPTOR-MEDIATED DELIVERY OF PHARMACOLOGICAL CHAPERONES. Comunicación en congreso. . .
Artículos publicados
Rocha, Gabriel;Muñoz-garcía, Juan C. ;Ramírez-cárdenas, Jonathan ;Padilla, María Del Carmen;Walpole, Samuel ;Nepravishta, Ridvan ;Garcia-Moreno, María Isabel;Sanchez-Fernández, Elena Matilde;Ortiz Mellet, Carmen;Angulo-Álvarez, Jesús:
Speeding-up the Determination of Protein Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR). Analytical Chemistry. 2024. Vol: 96. Pág. 615-619. 10.1021/acs.analchem.3c03980.
Speeding-up the Determination of Protein Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR). Analytical Chemistry. 2024. Vol: 96. Pág. 615-619. 10.1021/acs.analchem.3c03980.
Gonçalves-pereira, Rita ;Figueiredo, Jose A. ; Lucas, Susana D.;Garcia-Moreno, María Isabel;Ortiz Mellet, Carmen;Rauter, Amelia P. ; Ismael, Maria I.:
Synthesis, Biological Evaluation, and Docking Studies of Open-Chain Carbohydrate Amides as Acetylcholinesterase Inhibitors. Medicinal Chemistry. 2023. Vol: 19. Pág. 570-577.
Synthesis, Biological Evaluation, and Docking Studies of Open-Chain Carbohydrate Amides as Acetylcholinesterase Inhibitors. Medicinal Chemistry. 2023. Vol: 19. Pág. 570-577.
González, Manuel;Herrera, Irene;Garcia-Moreno, María Isabel;Ashmus, Roger A.;Vocadlo, David J.;Garcia-Fernandez, Jose Manuel;Nanba, Eiji;Higaki, Katsumi;Ortiz Mellet, Carmen:
sp2-Iminosugars targeting human lysosomal b-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease. Journal of Enzyme Inhibition and Medicinal Chemistry. 2022. Vol: 37. Núm: 1. Pág. 1364-1374. 10.1080/14756366.2022.2073444.
sp2-Iminosugars targeting human lysosomal b-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease. Journal of Enzyme Inhibition and Medicinal Chemistry. 2022. Vol: 37. Núm: 1. Pág. 1364-1374. 10.1080/14756366.2022.2073444.
Herrera, Irene;González, Manuel;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen:
Stereoselective Synthesis of Nojirimycin a-C-glycosides from a bicyclic acyliminium intermediate: A convenient entry to N,C-biantennary glycomimetics. ACS Omega. 2022. Vol: 7. Pág. 22394-22405. 10.1021/acsomega.2c01469.
Stereoselective Synthesis of Nojirimycin a-C-glycosides from a bicyclic acyliminium intermediate: A convenient entry to N,C-biantennary glycomimetics. ACS Omega. 2022. Vol: 7. Pág. 22394-22405. 10.1021/acsomega.2c01469.
Herrera, Irene;González, Manuel;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel:
Stereoselective Synthesis of Nojirimycin ¿¿C¿Glycosides from a Bicyclic Acyliminium Intermediate: A Convenient Entry to N,C¿Biantennary Glycomimetics. ACS Omega. 2022. Vol: 7. Pág. 22394-22405. 10.1021/acsomega.2c01469.
Stereoselective Synthesis of Nojirimycin ¿¿C¿Glycosides from a Bicyclic Acyliminium Intermediate: A Convenient Entry to N,C¿Biantennary Glycomimetics. ACS Omega. 2022. Vol: 7. Pág. 22394-22405. 10.1021/acsomega.2c01469.
Lumbroso, Alexandre;Berthonneau, Cle¿ment;Beaudet, Isabelle;Quintard, Jean-paul;Planchat, Aure¿lien;Garcia-Moreno, María Isabel;Ortiz Mellet, Carmen;Le Grognec, Erwan:
A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors. Organic and Biomolecular Chemistry. 2021. Vol: 19. Pág. 1083-1099. 10.1039/d0ob02249g.
A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors. Organic and Biomolecular Chemistry. 2021. Vol: 19. Pág. 1083-1099. 10.1039/d0ob02249g.
Sanchez-Fernández, Elena Matilde;Garcia-Moreno, María Isabel;García-Hernández, Raquel;Padrón, José M.;Garcia-Fernandez, Jose Manuel;Gamarro-Conde, Francisco;Ortiz Mellet, Carmen:
Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids. Molecules. 2019. Vol: 24. 10.3390/molecules24162882.
Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids. Molecules. 2019. Vol: 24. 10.3390/molecules24162882.
Sanchez-Fernández, Elena Matilde;Masgrau, Laura;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen;Garcia-Moreno, María Isabel;Arroba, Ana I.;Aguilar-Diosdado, Manuel;Padrón, José M.;García-Hernández, Raquel;Gamarro-Conde, Francisco;Fustero, Santos;Sánchez-aparicio, Jose Emilio:
Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and a. European Journal of Medicinal Chemistry. 2019. Vol: 182. 10.1016/j.ejmech.2019.111604.
Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and a. European Journal of Medicinal Chemistry. 2019. Vol: 182. 10.1016/j.ejmech.2019.111604.
Nierengarten, Jean-françois;Compain, Philippe;Schneider, Jérémy P.;Trinh, Thi Minh Nguyet;Joosten, Antoine;Holler, Michel;Lepage, Mathieu L.;Bodlenner, Anne;Garcia-Moreno, María Isabel;Ortiz Mellet, Carmen:
Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell. Chemistry: A European Journal. 2018. Vol: 24. Pág. 2483-2492. 10.1002/chem.201705600.
Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell. Chemistry: A European Journal. 2018. Vol: 24. Pág. 2483-2492. 10.1002/chem.201705600.
Mena-Barragán, Teresa;Ortiz Mellet, Carmen;Garcia-Moreno, María Isabel;Sevšek, Alen;Okazaki, Tetsuya;Nanba, Eiji;Higaki, Katsumi;Martin, Nathaniel I.;Pieters, Roland J.;Garcia-Fernandez, Jose Manuel:
Probing the inhibitor versus chaperone properties of sp2-iminosugars towards human ß-glucocerebrosidase: A picomolar chaperone for Gaucher disease. Molecules. 2018. Vol: 23. Núm: 927. 10.3390/molecules23040927.
Probing the inhibitor versus chaperone properties of sp2-iminosugars towards human ß-glucocerebrosidase: A picomolar chaperone for Gaucher disease. Molecules. 2018. Vol: 23. Núm: 927. 10.3390/molecules23040927.
Trinh, Thi Minh Nguyet;Holler, Michel;Schneider, Jérêmy P.;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Bodlenner, Anne;Compain, Philippe;Ortiz Mellet, Carmen;Nierengarten, Jean-françois:
Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers. Journal of Materials Chemistry B. 2017. Vol: 5. Pág. 6546-6556. 10.1039/C7TB01052D.
Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers. Journal of Materials Chemistry B. 2017. Vol: 5. Pág. 6546-6556. 10.1039/C7TB01052D.
Cano, María Emilia;Varela, Oscar;Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Kovensky, José;Uhrig, María Laura:
Synthesis of b-galactosylamides as ligands of the peanut lectin. Insights into the recognition process. Carbohydrate Research. 2017. Vol: 443-444. Pág. 58-67. 10.1016/j.carres.2017.03.018.
Synthesis of b-galactosylamides as ligands of the peanut lectin. Insights into the recognition process. Carbohydrate Research. 2017. Vol: 443-444. Pág. 58-67. 10.1016/j.carres.2017.03.018.
Garcia-Moreno, María Isabel;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen;De La Mata-Fernández, Mario;Sanchez-Fernández, Elena Matilde;Benito-Hernandez, Juan Manuel;Díaz-Quintana, Antonio;Fustero, Santos;Nanba, Eiji;Higaki, Katsumi;Sánchez-Alcázar, José Antonio:
Fluorinated Chaperone ß-Cyclodextrin Formulations for ß-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease. Journal of Medicinal Chemistry. 2017. Vol: 60. Pág. 1829-1842. 10.1021/acs.jmedchem.6b01550.
Fluorinated Chaperone ß-Cyclodextrin Formulations for ß-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease. Journal of Medicinal Chemistry. 2017. Vol: 60. Pág. 1829-1842. 10.1021/acs.jmedchem.6b01550.
Garcia-Moreno, María Isabel;Ortega-Caballero, Fernando;Rísquez-Cuadro, Rocío;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
The impact of heteromultivalency in lectin recognition and glycosidase inhibition: An integrated mechanistic study. Chemistry: A European Journal. 2017. Vol: 231. Pág. 6295-6304. 10.1002/chem.201700470.
The impact of heteromultivalency in lectin recognition and glycosidase inhibition: An integrated mechanistic study. Chemistry: A European Journal. 2017. Vol: 231. Pág. 6295-6304. 10.1002/chem.201700470.
Mena-Barragán, Teresa;Garcia-Moreno, María Isabel;Nanba, Eiji;Higaki, Katsumi;Concia, Alda Lisa;Clapés, Pere;Garcia-Fernandez, Jose Manuel;Ortiz Mellet, Carmen:
Inhibitor versus chaperone behaviour of D-fagomine, DAB and LAB sp2-iminosugar conjugates against glycosidases: A structure activity relationship stud. European Journal of Medicinal Chemistry. 2016. Vol: 121. Pág. 880-891. 10.1016/j.ejmech.2015.08.038.
Inhibitor versus chaperone behaviour of D-fagomine, DAB and LAB sp2-iminosugar conjugates against glycosidases: A structure activity relationship stud. European Journal of Medicinal Chemistry. 2016. Vol: 121. Pág. 880-891. 10.1016/j.ejmech.2015.08.038.
Abellán-flos, Marta;Garcia-Moreno, María Isabel;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Nierengarten, Jean-francois;Vincent, Stéphane P.:
Potent glycosidase inhibition with heterovalent fullerenes: unveiling the binding modes triggering multivalent inhibition. Chemistry: A European Journal. 2016. Vol: 22. Pág. 11450-11460. 10.1002/chem.201601673.
Potent glycosidase inhibition with heterovalent fullerenes: unveiling the binding modes triggering multivalent inhibition. Chemistry: A European Journal. 2016. Vol: 22. Pág. 11450-11460. 10.1002/chem.201601673.
Stauffert, Fabien;Bodlenner, Anne;Nguyen Trinh, Thi Minh;Ortiz Mellet, Carmen;Garcia-Moreno, María Isabel;Nierengarten, Jean-françois;Compain, Philippe:
Understanding multivalent effects in glycosidase inhibition using C-glycoside click clusters as molecular probes. New Journal of Chemistry. 2016. Vol: 40. Pág. 7421-7430. 10.1039/c6nj01311b.
Understanding multivalent effects in glycosidase inhibition using C-glycoside click clusters as molecular probes. New Journal of Chemistry. 2016. Vol: 40. Pág. 7421-7430. 10.1039/c6nj01311b.
Rodríguez- Lavado, Julio;Ohno, Kousaku;Suzuki, Yoshiyuki;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel;De La Mata-Fernández, Mario;Jimenez-Blanco, Jose Luis;Garcia-Moreno, María Isabel;Benito-Hernandez, Juan Manuel;Díaz-Quintana, Antonio;Sánchez-Alcázar, José Antonio;Higaki, Katsumi;Namba, Eiji:
Targeted Delivery of Pharmacological Chaperones for Gaucher Disease to Macrophages by a Mannosylated Cyclodextrin Carrier. Organic and Biomolecular Chemistry. 2014. Vol: 12. Pág. 2289-2301. 10.1039/C3OB42530D .
Targeted Delivery of Pharmacological Chaperones for Gaucher Disease to Macrophages by a Mannosylated Cyclodextrin Carrier. Organic and Biomolecular Chemistry. 2014. Vol: 12. Pág. 2289-2301. 10.1039/C3OB42530D .
Balbuena-Oliva, Patricia;Gonçalvez-pereira, Rita;Jimenez-Blanco, Jose Luis;Garcia-Moreno, María Isabel;Lesur, David;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
o-Xylylene Protecting Group in Carbohydrate Chemistry: Application to the Regioselective Protection of a Single vic-Diol Segment in Cyclodextrins. The Journal of Organic Chemistry. 2013. Vol: 78. Núm: 4. Pág. 1390-1403. 10.1021/jo302178f.
o-Xylylene Protecting Group in Carbohydrate Chemistry: Application to the Regioselective Protection of a Single vic-Diol Segment in Cyclodextrins. The Journal of Organic Chemistry. 2013. Vol: 78. Núm: 4. Pág. 1390-1403. 10.1021/jo302178f.
Alfonso, Pilar;Garcia-Fernandez, Jose Manuel;Giraldo, Pilar;Andreu, Vanesa;Pino-angeles, Almudena;Moya-garcia, Aurelio A.;Garcia-Moreno, María Isabel;Roduiguez-rey, Jose C.;Sanchez-jimenez, Francisca;Pocovi, Miguel;Ortiz Mellet, Carmen:
Bicyclic Derivatives of l-Idonojirimycin as Pharmacological Chaperones for Neuronopathic Forms of Gaucher Disease. ChemBioChem. 2013. Vol: 14. Núm: 8. Pág. 943-949. 10.1002/cbic.201200708.
Bicyclic Derivatives of l-Idonojirimycin as Pharmacological Chaperones for Neuronopathic Forms of Gaucher Disease. ChemBioChem. 2013. Vol: 14. Núm: 8. Pág. 943-949. 10.1002/cbic.201200708.
Takai, Tomoko;Sakakibara, Yasubumi;Ohno, Kousaku;Nanba, Eiji;Ortiz Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Suzuki, Yoshiyuki;Higaki, Katsumi;Aguilar-Moncayo, Matilde;Mena-Barragán, Teresa;Hirano, Yuki;Yura, Kei;Yu, Liang;Ninomiya, Haruka;Garcia-Moreno, María Isabel:
A Bicyclic 1-Deoxygalactonojirimycin Derivative as a Novel Pharmacological Chaperone for GM1 Gangliosidosis. Molecular Therapy. 2013. Vol: 21. Núm: 3. Pág. 526-532. 10.1038/mt.2012.263.
A Bicyclic 1-Deoxygalactonojirimycin Derivative as a Novel Pharmacological Chaperone for GM1 Gangliosidosis. Molecular Therapy. 2013. Vol: 21. Núm: 3. Pág. 526-532. 10.1038/mt.2012.263.
Brissonnet, Yoan;Gouin, Sébastien G.;Ortiz Mellet, Carmen;Morandat, Sandrine;Garcia-Moreno, María Isabel;Deniaud, David;Deniaud, Susan E.;Vidal, Sebastien;Sestak, Sergej;El Kirat, Karim:
Topological effects and binding modes operating with multivalent imino-sugar-based glycoclusters and mannosidases. Journal of the American Chemical Society. 2013. Vol: 135. Pág. 18427-18435. 10.1021/ja406931w.
Topological effects and binding modes operating with multivalent imino-sugar-based glycoclusters and mannosidases. Journal of the American Chemical Society. 2013. Vol: 135. Pág. 18427-18435. 10.1021/ja406931w.
Aguilar-Moncayo, Matilde;Díaz-Pérez, Paula;Garcia-Fernandez, Jose Manuel;Ortiz-Mellet, Carmen;Garcia-Moreno, María Isabel:
Synthesis and glycosidase inhibitory activity of isourea-type bicyclic sp2-iminosugars related to galactonojirimycin and allonojirimycin. Tetrahedron. 2012. Vol: 68. Núm: 2. Pág. 681-689. 10.1016/j.tet.2011.10.091.
Synthesis and glycosidase inhibitory activity of isourea-type bicyclic sp2-iminosugars related to galactonojirimycin and allonojirimycin. Tetrahedron. 2012. Vol: 68. Núm: 2. Pág. 681-689. 10.1016/j.tet.2011.10.091.
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ishii, S;Sakakibara, Y;Ohno, Katsumi;Nanba, E.;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Suzuki, Y;Takai, T;Higaki, K;Mena-Barragán, Teresa;Hirano, Y;Yura, K;Li, Linying;Yu, Y;Ninomiya, H:
Tuning glycosidase inhibition through aglycone interactions: pharmacological chaperones for Fabry disease and GM(1) gangliosidosis. Chemical Communications. 2012. Vol: 48. Núm: 52. Pág. 6514-6516. 10.1039/c2cc32065g .
Tuning glycosidase inhibition through aglycone interactions: pharmacological chaperones for Fabry disease and GM(1) gangliosidosis. Chemical Communications. 2012. Vol: 48. Núm: 52. Pág. 6514-6516. 10.1039/c2cc32065g .
Diot, Jennifer;Garcia-Moreno, María Isabel;Twigg, Gabrielle;Ortiz-Mellet, Carmen;Haupt, Karsten;Butters, Terry D;Kovenski, José;Gouin, Sebastien G:
AMPHIPHILIC 1-DEOXYNOJIRIMYCIN DERIVATIVES THROUGH CLICK STRATEGIES FOR CHEMICAL CHAPERONING IN N370S GAUCHER CELLS. The Journal of Organic Chemistry. 2011. Vol: 76. Pág. 7757-7768. 10.1021/jo201125x.
AMPHIPHILIC 1-DEOXYNOJIRIMYCIN DERIVATIVES THROUGH CLICK STRATEGIES FOR CHEMICAL CHAPERONING IN N370S GAUCHER CELLS. The Journal of Organic Chemistry. 2011. Vol: 76. Pág. 7757-7768. 10.1021/jo201125x.
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Trapero, Ana ;Egido-gabás, Meritxell;Llebaria-Soldevilla, Amadeu;Garcia-Fernandez, Jose Manuel;Ortiz-Mellet, Carmen:
BICYCLIC (GALACTO)NOJIRIMYCIN ANALOGUES AS GLYCOSIDASE INHIBITORS: EFFECT OF STRUCTURAL MODIFICATIONS IN THEIR PHARMACOLOGICAL CHAPERONE POTENTIAL TOW. Organic and Biomolecular Chemistry. 2011. Vol: 9. Pág. 3698-3713. 10.1039/c1ob05234a.
BICYCLIC (GALACTO)NOJIRIMYCIN ANALOGUES AS GLYCOSIDASE INHIBITORS: EFFECT OF STRUCTURAL MODIFICATIONS IN THEIR PHARMACOLOGICAL CHAPERONE POTENTIAL TOW. Organic and Biomolecular Chemistry. 2011. Vol: 9. Pág. 3698-3713. 10.1039/c1ob05234a.
Luan-,Z;Higaki-,K;Suzuki-,Y.;Aguilar-Moncayo, Matilde;Li-,Linjing;Ninomiya-,Haruaki;Nanba-,Eiji;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Ohno-,K;Garcia-Fernandez, Jose Manuel:
A FLUORESCENT SP2-IMINOSUGAR WITH PHARMACOLOGICAL CHAPERONE ACTIVITY FOR GAUCHER DISEASE: SYNTHESIS AND INTRACELLULAR DISTRIBUTION STUDIES. ChemBioChem. 2010. Vol: 11. Pág. 2453-2464. 10.1002/cbic.201000323.
A FLUORESCENT SP2-IMINOSUGAR WITH PHARMACOLOGICAL CHAPERONE ACTIVITY FOR GAUCHER DISEASE: SYNTHESIS AND INTRACELLULAR DISTRIBUTION STUDIES. ChemBioChem. 2010. Vol: 11. Pág. 2453-2464. 10.1002/cbic.201000323.
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Stutz-,Arnold E.;Garcia-Fernandez, Jose Manuel;Wrodnigg-,Tanja M.;Ortiz-Mellet, Carmen:
FLUORESCENT-TAGGED SP2-IMINOSUGARS WITH POTENT B-GLUCOSIDASE INHIBITORY ACTIVITY. Bioorganic & Medicinal Chemistry. 2010. Vol: 18. Pág. 7439-7455. 10.1016/j.bmc.2010.09.003.
FLUORESCENT-TAGGED SP2-IMINOSUGARS WITH POTENT B-GLUCOSIDASE INHIBITORY ACTIVITY. Bioorganic & Medicinal Chemistry. 2010. Vol: 18. Pág. 7439-7455. 10.1016/j.bmc.2010.09.003.
Diot-,Jennifer;Garcia-Moreno, María Isabel;Gouin-,Sebastien;Ortiz-Mellet, Carmen;Haupt-,Karsten;Kovensky-,José:
MULTIVALENT IMINOSUGARS TO MODULATE AFFINITY AND SELECTIVITY FOR GLYCOSIDASES. Organic and Biomolecular Chemistry. 2009. Vol: 7. Núm: 2. Pág. 357-363.
MULTIVALENT IMINOSUGARS TO MODULATE AFFINITY AND SELECTIVITY FOR GLYCOSIDASES. Organic and Biomolecular Chemistry. 2009. Vol: 7. Núm: 2. Pág. 357-363.
Sanchez-Fernández, Elena Matilde;Rísquez-Cuadro, Rocío;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
GENERALIZED ANOMERIC EFFECT IN GEM-DIAMINES: STEREOSELECTIVE SYNTHESIS OF ALFA-N-LINKED DISACCHARIDE MIMICS. Organic Letters. 2009. Vol: 11. Núm: 15. Pág. 3306-3309.
GENERALIZED ANOMERIC EFFECT IN GEM-DIAMINES: STEREOSELECTIVE SYNTHESIS OF ALFA-N-LINKED DISACCHARIDE MIMICS. Organic Letters. 2009. Vol: 11. Núm: 15. Pág. 3306-3309.
Benltifa-,Mahmoud;De Kiss-,Miklos;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Gueyrard-,David;Wadouachi-,Anne:
REGIOSELECTIVE SYNTHESIS AND BIOLOGICAL EVALUATION OF SPIRO-SULFAMIDATE GLYCOSIDES FROM EXO-GLYCALS. Tetrahedron: Asymmetry. 2009. Vol: 20. Pág. 1817-1823. 10.1016/j.tetasy.2009.07.012.
REGIOSELECTIVE SYNTHESIS AND BIOLOGICAL EVALUATION OF SPIRO-SULFAMIDATE GLYCOSIDES FROM EXO-GLYCALS. Tetrahedron: Asymmetry. 2009. Vol: 20. Pág. 1817-1823. 10.1016/j.tetasy.2009.07.012.
Luan-,Z;Aguilar-Moncayo, Matilde;Ohno-,K;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Suzuki-,Y.:
CHAPERONE ACTIVITY OF BICYCLIC NOJIRIMYCIN ANALOGUES FOR GAUCHER MUTATIONS IN COMPARISON WITH N-(N-NONYL)DEOXYNOJIRIMYCIN. ChemBioChem. 2009. Vol: 10. Pág. 2780-2792. 10.1002/cbic.200900442.
CHAPERONE ACTIVITY OF BICYCLIC NOJIRIMYCIN ANALOGUES FOR GAUCHER MUTATIONS IN COMPARISON WITH N-(N-NONYL)DEOXYNOJIRIMYCIN. ChemBioChem. 2009. Vol: 10. Pág. 2780-2792. 10.1002/cbic.200900442.
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS OF THIOHYDANTOIN-CASTANOSPERMINE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. The Journal of Organic Chemistry. 2009. Vol: 74. Pág. 3595-3598.
SYNTHESIS OF THIOHYDANTOIN-CASTANOSPERMINE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. The Journal of Organic Chemistry. 2009. Vol: 74. Pág. 3595-3598.
Brumshtein-,Boris;Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Silman-,Israel;Shaaltiel-,Joseph;Aviezer-,David;Sussman-,Joel L.;Futerman-,Anthony H.:
6-AMINO-6-DEOXY-5,6-DI-N-(N '-OCTYLIMINOMETHYLIDENE)NOJIRIMYCIN: SYNTHESIS, BIOLOGICAL EVALUATION, AND CRYSTAL STRUCTURE IN COMPLEX WITH ACID BETA-GLU. ChemBioChem. 2009. Vol: 10. Núm: 9. Pág. 1480-1485.
6-AMINO-6-DEOXY-5,6-DI-N-(N '-OCTYLIMINOMETHYLIDENE)NOJIRIMYCIN: SYNTHESIS, BIOLOGICAL EVALUATION, AND CRYSTAL STRUCTURE IN COMPLEX WITH ACID BETA-GLU. ChemBioChem. 2009. Vol: 10. Núm: 9. Pág. 1480-1485.
Aguilar-Moncayo, Matilde;Gloster-,Tracey M.;Turkenburg-,Johan P.;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Davies-,Gideon J;Garcia-Fernandez, Jose Manuel:
GLYCOSIDASE INHIBITION BY RING-MODIFIED CASTANOSPERMINE ANALOGUES: TACKLING ENZYME SELECTIVITY BY INHIBITOR TAILORING. Organic and Biomolecular Chemistry. 2009. Vol: 7. Pág. 2738-2747. 10.1039/b906968b.
GLYCOSIDASE INHIBITION BY RING-MODIFIED CASTANOSPERMINE ANALOGUES: TACKLING ENZYME SELECTIVITY BY INHIBITOR TAILORING. Organic and Biomolecular Chemistry. 2009. Vol: 7. Pág. 2738-2747. 10.1039/b906968b.
Louis-,Farida;Garcia-Moreno, María Isabel;Balbuena-Oliva, Patricia;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
STEREOSELECTIVE SYNTHESIS OF NONSYMMETRICAL DIFRUCTOSE DIANHYDRIDES FROM XYLYLENE-TETHERED D-FRUCTOSE PRECURSORS. Tetrahedron. 2008. Vol: 64. Núm: 12. Pág. 2792-2800.
STEREOSELECTIVE SYNTHESIS OF NONSYMMETRICAL DIFRUCTOSE DIANHYDRIDES FROM XYLYLENE-TETHERED D-FRUCTOSE PRECURSORS. Tetrahedron. 2008. Vol: 64. Núm: 12. Pág. 2792-2800.
Aguilar-Moncayo, Matilde;Díaz-Pérez, Paula;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND BIOLOGICAL EVALUATION OF GUANIDINE-TYPE IMINOSUGARS. The Journal of Organic Chemistry. 2008. Vol: 73. Núm: 5. Pág. 1995-1998.
SYNTHESIS AND BIOLOGICAL EVALUATION OF GUANIDINE-TYPE IMINOSUGARS. The Journal of Organic Chemistry. 2008. Vol: 73. Núm: 5. Pág. 1995-1998.
Aguilar-Moncayo, Matilde;Gloster-,Tracey M.;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Davies-,Gideon J;Llebaria-Soldevilla, Amadeu;Casas-Brugulat, Josefina;Egido-Gabás-, Meritxell;Garcia-Fernandez, Jose Manuel:
MOLECULAR BASIS FOR BETA-GLUCOSIDASE INHIBITION BY RING-MODIFIED CALYSTEGINE ANALOGUES. ChemBioChem. 2008. Vol: 9. Núm: 16. Pág. 2612-2618.
MOLECULAR BASIS FOR BETA-GLUCOSIDASE INHIBITION BY RING-MODIFIED CALYSTEGINE ANALOGUES. ChemBioChem. 2008. Vol: 9. Núm: 16. Pág. 2612-2618.
Garcia-Moreno, María Isabel;Benito-Hernandez, Juan Manuel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
CHEMICAL AND ENZYMATIC APPROACHES TO CARBOHYDRATE-DERIVED SPIROKETALS: DI-D-FRUCTOSE DIANHYDRIDES (DFAS). Molecules. 2008. Vol: 13. Núm: 8. Pág. 1640-1670.
CHEMICAL AND ENZYMATIC APPROACHES TO CARBOHYDRATE-DERIVED SPIROKETALS: DI-D-FRUCTOSE DIANHYDRIDES (DFAS). Molecules. 2008. Vol: 13. Núm: 8. Pág. 1640-1670.
Benltifa-,Mahmoud;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel;Wadouachi-,Anne:
SYNTHESIS AND EVALUATION OF SULFAMIDE-TYPE INDOLIZIDINES AS GLYCOSIDASE INHIBITORS. Bioorganic & Medicinal Chemistry Letters. 2008. Vol: 18. Núm: 9. Pág. 2805-2808.
SYNTHESIS AND EVALUATION OF SULFAMIDE-TYPE INDOLIZIDINES AS GLYCOSIDASE INHIBITORS. Bioorganic & Medicinal Chemistry Letters. 2008. Vol: 18. Núm: 9. Pág. 2805-2808.
Collot-,Mayeul;Garcia-Moreno, María Isabel;Fajolles-,Christophe;Roux-,Michel;Mauclaire-,Laurent;Mallet-,Jean-Maurice:
BIS AMPHIPHILIC ANTENNAE CYCLODEXTRINS: THE FIRST EXAMPLES. Tetrahedron Letters. 2007. Vol: 48. Núm: 48. Pág. 8566-8569.
BIS AMPHIPHILIC ANTENNAE CYCLODEXTRINS: THE FIRST EXAMPLES. Tetrahedron Letters. 2007. Vol: 48. Núm: 48. Pág. 8566-8569.
Louis-,Farida;Garcia-Moreno, María Isabel;Balbuena-Oliva, Patricia;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SPACER-MEDIATED SYNTHESIS OF BIS-SPIROKETAL DISACCHARIDES: NONSYMMETRICAL FURANOSE-PYRANOSE DIFRUCTOSE DIANHYDRIDES. Synlett. 2007. Vol: 17. Pág. 2738-2742.
SPACER-MEDIATED SYNTHESIS OF BIS-SPIROKETAL DISACCHARIDES: NONSYMMETRICAL FURANOSE-PYRANOSE DIFRUCTOSE DIANHYDRIDES. Synlett. 2007. Vol: 17. Pág. 2738-2742.
Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND BIOLOGICAL EVALUATION OF 6-OXA-NOR-TROPANE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. Tetrahedron. 2007. Vol: 63. Núm: 33. Pág. 7879-7884.
SYNTHESIS AND BIOLOGICAL EVALUATION OF 6-OXA-NOR-TROPANE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. Tetrahedron. 2007. Vol: 63. Núm: 33. Pág. 7879-7884.
Aguilar-Moncayo, Matilde;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
INTRAMOLECULAR BENZYL PROTECTION DELIVERY: A PRACTICAL SYNTHESIS OF DMDP AND DGDP FROM D-FRUCTOSE. Organic Letters. 2006. Vol: 8. Núm: 2. Pág. 297-299.
INTRAMOLECULAR BENZYL PROTECTION DELIVERY: A PRACTICAL SYNTHESIS OF DMDP AND DGDP FROM D-FRUCTOSE. Organic Letters. 2006. Vol: 8. Núm: 2. Pág. 297-299.
Rubio-Castillo, Enrique Miguel;Garcia-Moreno, María Isabel;Balbuena-Oliva, Patricia;Lahoz-,Fernando J.;Alvarez-Gonzalez, Eleuterio;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SPACER-MEDIATED SYNTHESIS OF CONTRA-THERMODYNAMIC SPIROACETALS: STEREOSELECTIVE SYNTHESIS OF C-2-SYMMETRIC DIFRUCTOSE DIANHYDRIDES. The Journal of Organic Chemistry. 2006. Vol: 71. Núm: 6. Pág. 2257-2266.
SPACER-MEDIATED SYNTHESIS OF CONTRA-THERMODYNAMIC SPIROACETALS: STEREOSELECTIVE SYNTHESIS OF C-2-SYMMETRIC DIFRUCTOSE DIANHYDRIDES. The Journal of Organic Chemistry. 2006. Vol: 71. Núm: 6. Pág. 2257-2266.
Périon-,Régis;Ferrières-,Vincent;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Duval-,Raphaël;Garcia-Fernandez, Jose Manuel:
1,2,3-TRIAZOLES AND RELATED GLYCOCONJUGATES AS NEW GLYCOSIDASE INHIBITORS. Tetrahedron. 2005. Vol: 61. Núm: 38. Pág. 9118-9128.
1,2,3-TRIAZOLES AND RELATED GLYCOCONJUGATES AS NEW GLYCOSIDASE INHIBITORS. Tetrahedron. 2005. Vol: 61. Núm: 38. Pág. 9118-9128.
Díaz-Pérez, Paula;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND COMPARATIVE GLYCOSIDASE INHIBITORY PROPERTIES OF REDUCING CASTANOSPERMINE ANALOGUES. European Journal Of Organic Chemistry. 2005. Núm: 14. Pág. 2903-2913.
SYNTHESIS AND COMPARATIVE GLYCOSIDASE INHIBITORY PROPERTIES OF REDUCING CASTANOSPERMINE ANALOGUES. European Journal Of Organic Chemistry. 2005. Núm: 14. Pág. 2903-2913.
Rubio-Castillo, Enrique Miguel;Garcia-Moreno, María Isabel;Balbuena-Oliva, Patricia;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
RIGID SPACER-MEDIATED SYNTHESIS OF BIS-SPIROKETAL RING SYSTEMS: STEREOSELECTIVE SYNTHESIS NONSYMMETRICAL SPIRO OF DISACCHARIDES. Organic Letters. 2005. Vol: 7. Núm: 4. Pág. 729-731.
RIGID SPACER-MEDIATED SYNTHESIS OF BIS-SPIROKETAL RING SYSTEMS: STEREOSELECTIVE SYNTHESIS NONSYMMETRICAL SPIRO OF DISACCHARIDES. Organic Letters. 2005. Vol: 7. Núm: 4. Pág. 729-731.
Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS OF CALYSTEGINE B-2, B-3, AND B-4 ANALOGUES: MAPPING THE STRUCTURE-GLYCOSIDASE INHIBITORY ACTIVITY RELATIONSHIPS IN THE 1-DEOXY-6-OXACALYSTEG. European Journal Of Organic Chemistry. 2004. Núm: 8. Pág. 1803-1819.
SYNTHESIS OF CALYSTEGINE B-2, B-3, AND B-4 ANALOGUES: MAPPING THE STRUCTURE-GLYCOSIDASE INHIBITORY ACTIVITY RELATIONSHIPS IN THE 1-DEOXY-6-OXACALYSTEG. European Journal Of Organic Chemistry. 2004. Núm: 8. Pág. 1803-1819.
Garcia-Moreno, María Isabel;Rodríguez-Lucena, David;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
PSEUDOAMIDE-TYPE PYRROLIDINE AND PYRROLIZIDINE GLYCOMIMETICS AND THEIR INHIBITORY ACTIVITIES AGAINST GLYCOSIDASES. The Journal of Organic Chemistry. 2004. Vol: 69. Núm: 10. Pág. 3578-3581.
PSEUDOAMIDE-TYPE PYRROLIDINE AND PYRROLIZIDINE GLYCOMIMETICS AND THEIR INHIBITORY ACTIVITIES AGAINST GLYCOSIDASES. The Journal of Organic Chemistry. 2004. Vol: 69. Núm: 10. Pág. 3578-3581.
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND EVALUATION OF ISOUREA-TYPE GLYCOMIMETICS RELATED TO THE INDOLIZIDINE AND TREHAZOLIN GLYCOSIDASE INHIBITOR FAMILIES. The Journal of Organic Chemistry. 2003. Vol: 68. Núm: 23. Pág. 8890-8901.
SYNTHESIS AND EVALUATION OF ISOUREA-TYPE GLYCOMIMETICS RELATED TO THE INDOLIZIDINE AND TREHAZOLIN GLYCOSIDASE INHIBITOR FAMILIES. The Journal of Organic Chemistry. 2003. Vol: 68. Núm: 23. Pág. 8890-8901.
Díaz-Pérez, Paula;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS OF (1S,2S,3R,8S,8AR)-1,2,3,8-TETRAHYDROXY-6-OXA-5- THIOXOINDOLIZIDINE: A STABLE REDUCING SWAINSONINE ANALOG WITH CONTROLLED ANOMERIC CONFIGU. Synlett. 2003. Núm: 3. Pág. 341-344.
SYNTHESIS OF (1S,2S,3R,8S,8AR)-1,2,3,8-TETRAHYDROXY-6-OXA-5- THIOXOINDOLIZIDINE: A STABLE REDUCING SWAINSONINE ANALOG WITH CONTROLLED ANOMERIC CONFIGU. Synlett. 2003. Núm: 3. Pág. 341-344.
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Benito-Hernandez, Juan Manuel;Ortiz-Mellet, Carmen;Defaye-,Jacques;Garcia-Fernandez, Jose Manuel:
ONE-STEP SYNTHESIS OF NON-ANOMERIC SUGAR ISOTHIOCYANATES FROM SUGAR AZIDES. Carbohydrate Research. 2002. Pág. ---.
ONE-STEP SYNTHESIS OF NON-ANOMERIC SUGAR ISOTHIOCYANATES FROM SUGAR AZIDES. Carbohydrate Research. 2002. Pág. ---.
Garcia-Moreno, María Isabel;Díaz-Pérez, Paula;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
CASTANOSPERMINE-TREHAZOLIN HYBRIDS: A NEW FAMILY OF GLYCOMIMETICS WITH TUNEABLE GLYCOSIDASE INHIBITORY PROPERTIES. Chemical Communications. 2002. Núm: 8. Pág. 848-849.
CASTANOSPERMINE-TREHAZOLIN HYBRIDS: A NEW FAMILY OF GLYCOMIMETICS WITH TUNEABLE GLYCOSIDASE INHIBITORY PROPERTIES. Chemical Communications. 2002. Núm: 8. Pág. 848-849.
Garcia-Moreno, María Isabel;Benito-Hernandez, Juan Manuel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
SYNTHESIS AND EVALUATION OF CALYSTEGINE B-2 ANALOGUES AS GLYCOSIDASE INHIBITORS. The Journal of Organic Chemistry. 2001. Vol: 66. Núm: 23. Pág. 7604-7614.
SYNTHESIS AND EVALUATION OF CALYSTEGINE B-2 ANALOGUES AS GLYCOSIDASE INHIBITORS. The Journal of Organic Chemistry. 2001. Vol: 66. Núm: 23. Pág. 7604-7614.
Díaz-Pérez, Víctor;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Fuentes-Mota, Jose;Díaz-Arribas,Juan Carlos;Cañada-, Javier;Garcia-Fernandez, Jose Manuel:
GENERALIZED ANOMERIC EFFECT IN ACTION: SYNTHESIS AND EVALUATION OF STABLE REDUCING INDOLIZIDINE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. The Journal of Organic Chemistry. 2000. Vol: 65. Núm: 1. Pág. 136-143.
GENERALIZED ANOMERIC EFFECT IN ACTION: SYNTHESIS AND EVALUATION OF STABLE REDUCING INDOLIZIDINE GLYCOMIMETICS AS GLYCOSIDASE INHIBITORS. The Journal of Organic Chemistry. 2000. Vol: 65. Núm: 1. Pág. 136-143.
Garcia-Moreno, María Isabel;Benito-Hernandez, Juan Manuel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
NITROGEN VERSUS SULFUR ACYLATION IN SUGAR THIOUREAS: REGIOSELECTIVITY AND CONFORMATIONAL CONSEQUENCES. Tetrahedron: Asymmetry. 2000. Vol: 11. Núm: 6. Pág. 1331-1341.
NITROGEN VERSUS SULFUR ACYLATION IN SUGAR THIOUREAS: REGIOSELECTIVITY AND CONFORMATIONAL CONSEQUENCES. Tetrahedron: Asymmetry. 2000. Vol: 11. Núm: 6. Pág. 1331-1341.
Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel:
POLYHYDROXYLATED N-(THIO)CARBAMOYL PIPERIDINES: NOJIRIMYCIN- TYPE GLYCOMIMETICS WITH CONTROLLED ANOMERIC CONFIGURATION. Tetrahedron: Asymmetry. 1999. Vol: 10. Núm: 22. Pág. 4271-4275.
POLYHYDROXYLATED N-(THIO)CARBAMOYL PIPERIDINES: NOJIRIMYCIN- TYPE GLYCOMIMETICS WITH CONTROLLED ANOMERIC CONFIGURATION. Tetrahedron: Asymmetry. 1999. Vol: 10. Núm: 22. Pág. 4271-4275.
Patentes
Alfonso-palacin, Pilar;Moya-García, Aurelio Ángel;Pino-Ángeles, Almudena;Sanchez-jimenez, Francisca;Pocoví-mieras, Miguel;Giraldo-castellano, Pilar;Garcia-Moreno, María Isabel;Ortiz-Mellet, Carmen;Garcia-Fernandez, Jose Manuel: Utilización de derivados bicíclicos de L-idonojirimicina para el tratamiento de la enfermedad de Gaucher. Número de patente:
Garcia-Fernandez, Jose Manuel;Ortiz-Mellet, Carmen;Garcia-Moreno, María Isabel;Aguilar-Moncayo, Matilde;Suzuki, Yoshiyuki;Ohno, Kousako: COMPUESTOS POTENCIADORES DE LA ACTIVIDAD DE GLICOSIDASAS MUTANTES. Número de patente: P200802988
Tesis dirigidas o codirigidas
Aguilar-Moncayo, Matilde:
Iminoazúcares sp2 como inhibidores de glicosidasas: aplicación al diseño de chaperonas químicas para el tratamiento de la enfermedad de Gaucher. Tesis Doctoral. 2010
Iminoazúcares sp2 como inhibidores de glicosidasas: aplicación al diseño de chaperonas químicas para el tratamiento de la enfermedad de Gaucher. Tesis Doctoral. 2010
