Guillén-Mancina, Emilio;Vega-Holm, Margarita;Garcia Lozano, María Del Rosario;Burgos-Morón, Estefanía;Mazzotta, Sarah;MARTINEZ-AGUADO, PABLO;Calderón-Montaño, José Manuel;Vega-Perez, Jose Manuel;López-Lázaro, Miguel;Iglesias-Guerra, Fernando:
Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2- substituted-piperazine Derivatives as Potential Anticancer Agents¿In Vitro Evaluation against Bre. International Journal of Molecular Sciences. 2023. Vol: 24. doi.org/10.3390/ijms242317041.
Jiménez Alonso, Julio José;Guillén-Mancina, Emilio;Calderón-Montaño, José Manuel;Jiménez-González, Víctor;Díaz, Patricia;Burgos-Morón, Estefanía;López-Lázaro, Miguel:
Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer. Nutrients. 2022. Vol: 14. https://doi.org/10.3390/ nu14163378.
Carrasco-Carrasco, Carlos Jesús;Montilla-Ramos, Francisco J.;Alvarez-Gonzalez, Eleuterio;Calderón-Montaño, José Manuel;López-Lázaro, Miguel;Galindo-Del Pozo, Agustin:
Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes. Journal of Inorganic Biochemistry. 2022. Vol: 235. 10.1016/j.jinorgbio.2022.111924.
López-Lázaro, Miguel:
Opium, street opium and cancer risk. Current Pharmaceutical Design. 2022. 10.2174/1381612828666220607104805 .
Burgos-Morón, Estefanía;López-Lázaro, Miguel;Calderón-Montaño, José Manuel;Pastor-Carrillo, Nuria María;Orta-Vázquez, Manuel Luis;Jiménez Alonso, Julio José;Palo-Nieto, Juan Carlos;Vega-Holm, Margarita;Vega-Perez, Jose Manuel;Iglesias-Guerra, Fernando;Mateos-Cordero, Santiago:
In Vitro Anticancer Activity and Mechanism of Action of an Aziridinyl Galactopyranoside. Biomedicines. 2022. Vol: 10. Núm: 1. doi.org/10.3390/biomedicines10010041.
García, Mónica C;Calderón-Montaño, José Manuel;Rueda-Rueda, Manuela;Longhi, Marcela;Rabasco-Alvarez, Antonio Maria;López-Lázaro, Miguel;Prieto-Dapena, Francisco;Gonzalez-Rodriguez, Maria Luisa:
pH-temperature dual-sensitive nucleolipid-containing stealth liposomes anchored with PEGylated AuNPs for triggering delivery of doxorubicin. International Journal of Pharmaceutics. 2022. Vol: 619. 10.1016/j.ijpharm.2022.121691.
Recio-Jiménez, Rocio;Organero, Juan Ángel ;Khiar-El Wahabi, Noureddine;Fernandez-Fernandez, Inmaculada;Lerena, Patricia;Pozo, Esther;Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;López-Lázaro, Miguel;Valdivia-Giménez, Victoria Esther;Pernia Leal, Manuel;Mouillac, Bernard :
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity. Journal of Medicinal Chemistry. 2021. Vol: 64. Núm: 14. Pág. 10350-10370. 10.1021/acs.jmedchem.1c00793.
Calderón-Montaño, José Manuel;López-Lázaro, Miguel;Martínez-sánchez, Sara Maria;Jiménez-González, Víctor;Burgos-Morón, Estefanía;Guillén-Mancina, Emilio;Jiménez Alonso, Julio José;Díaz-ortega , Patricia ;García-Martín, Felipe José;Aparicio-Martínez, Abelardo:
Screening for Selective Anticancer Activity of 65 Extracts of Plants Collected in Western Andalusia, Spain. Plants. 2021. Vol: 10. Núm: 10. 10.3390/plants10102193..
García, Mónica C.;Gonzalez-Rodriguez, Maria Luisa;Naitlho, Nabila;Calderón-Montaño, José Manuel;Drago, Estrella;Rueda-Rueda, Manuela;Longui, Marcela ;Rabasco-Alvarez, Antonio Maria;López-Lázaro, Miguel;Prieto-Dapena, Francisco:
Cholesterol Levels Affect the Performance of AuNPs-Decorated Thermo-Sensitive Liposomes as Nanocarriers for Controlled Doxorubicin Delivery. Pharmaceutics. 2021. 10.3390/pharmaceutics13070973.
Zbakh-, Hanaa;Zubía-Mendoza, Eva;De Los Reyes-Jiménez, Carolina;Calderón-Montaño, José Manuel;López-Lázaro, Miguel;Motilva-Sánchez, Virginia:
Meroterpenoids from the Brown Alga Cystoseira usneoides as Potential Anti-Inflammatory and Lung Anticancer Agents. Marine Drugs. 2020. Vol: 18. Núm: 207. Pág. 1-16. 10.3390/md18040207.
Romero, Elena;Mena-Barragán, Teresa;García-de Dionisio, Elena;Sanchez-Fernández, Elena Matilde;Garcia-Fernandez, Jose Manuel;Guillén-Mancina, Emilio;López-Lázaro, Miguel;Khiar-El Wahabi, Noureddine:
Mannose-coated polydiacetylene (PDA)-basednanomicelles: synthesis, interaction withconcanavalin A and application in the watersolubilization and deliv. Journal of Materials Chemistry B. 2019. Vol: 7. Pág. 5930-5946. 10.1039/c9tb01218d.
Burgos-Morón, Estefanía;Calderón-Montaño, José Manuel;Pastor-Carrillo, Nuria María;Orta-Vázquez, Manuel Luis;Jiménez Alonso, Julio José;Vega-Holm, Margarita;Vega-Perez, Jose Manuel;Iglesias-Guerra, Fernando;López-Lázaro, Miguel:
Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside. Drug Development Research. 2018. Vol: 79. Pág. 426-436. 10.1002/ddr.21483.
Jiménez Alonso, Julio José;Calderón-Montaño, José Manuel;López-Lázaro, Miguel:
Are most cancer cases a consequence of an immune deficiency caused by thymic involution?. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2018. Vol: 115. Núm: 19. Pág. E4314-E4315. 10.1073/pnas.1803180115.
Burgos-Morón, Estefanía;Mateos-Cordero, Santiago;Orta-Vázquez, Manuel Luis;Calderón-Montaño, José Manuel;Pastor-Carrillo, Nuria María; Höglund, Andreas;Ruiz-castizo, Ángel;Domínguez-García, Inmaculada;López-Lázaro, Miguel;Hajji, Nadil;Helleday, Thomas:
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2'-deoxycytidine-induced DNA lesions. Oncotarget. 2018. Vol: 80. Núm: 9. Pág. 35069-35084. 10.18632/oncotarget.26189.
López-Lázaro, Miguel:
The stem cell division theory of cancer. . Critical Reviews in Oncology/Hematology. 2018. Vol: 123. Pág. 95-113. 10.1016/j.critrevonc.2018.01.010.
Guillén-Mancina, Emilio;Calderón-Montaño, José Manuel;López-Lázaro, Miguel:
Avoiding the ingestion of cytotoxic concentrations of ethanol may reduce the risk of cancer associated with alcohol consumption. Drug and Alcohol Dependence. 2018. Núm: 183. Pág. 201-204. 10.1016/j.drugalcdep.2017.11.013.
Calderón-Montaño, José Manuel;Martinez-sánchez, Sara;Burgos-Morón, Estefanía;Guillén-Mancina, Emilio;Jiménez Alonso, Julio José;García , Felipe;Aparicio-Martínez, Abelardo;López-Lázaro, Miguel:
Screening for selective anticancer activity of plants from Grazalema Natural Park, Spain. Natural Product Research. 2018. 10.1080/14786419.2018.1480620.
López-Lázaro, Miguel:
Cancer etiology: Variation in cancer risk among tissues is poorly explained by the number of gene mutations. Genes Chromosomes & Cancer. 2018. Vol: 57. Núm: 6. Pág. 281-293. 10.1002/gcc.22530 .
Calderón-Montaño, José Manuel;Jiménez Alonso, Julio José;Guillén-Mancina, Emilio;Burgos-Morón, Estefanía;López-Lázaro, Miguel:
A 30-s exposure to ethanol 20% is cytotoxic to human keratinocytes: possible mechanistic link between alcohol-containing mouthwashes and oral cancer. Clinical Oral Investigations. 2018. Vol: 22. Núm: 8. Pág. 2943-2946. 10.1007/s00784-018-2602-z.
Orta-Vázquez, Manuel Luis;Pastor-Carrillo, Nuria María;Burgos-Morón, Estefanía;Domínguez-García, Inmaculada;Calderón-Montaño, José Manuel;Huertas-castaño, Carlos;López-Lázaro, Miguel;Helleday, Thomas;Mateos-Cordero, Santiago:
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination.. DNA Repair. 2017. Vol: 57. Pág. 116-124. 10.1016/j.dnarep.2017.07.002.
Recio-Jiménez, Rocio;VENGUT-CLIMENT, EMPAR;Mouillac, Bernard;Orcel, Helene;López-Lázaro, Miguel;Calderón-Montaño, José Manuel;Alvarez-Gonzalez, Eleuterio;Khiar-El Wahabi, Noureddine;Fernandez-Fernandez, Inmaculada:
Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran cor. European Journal of Medicinal Chemistry. 2017. Vol: 138. Pág. 644-660.
López-Lázaro, Miguel:
A local mechanism by which alcohol consumption causes cancer. Oral Oncology. 2016. Vol: 62. Pág. 149-152. https://doi.org/10.1016/j.oraloncology.2016.10.001.
Burgos-Morón, Estefanía;Calderón-Montaño, José Manuel;Orta-Vázquez, Manuel Luis;Guillén-Mancina, Emilio;López-Lázaro, Miguel:
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid.. Toxins. 2016. Vol: 8. Núm: 7. 10.3390/toxins8070211 .
Mate-Barrero, Alfonso;Ruiz-Armenta, Maria Victoria;Aguilar-espejo, Gema;Reyes-goya, Claudia;Miguel-Carrasco, Jose Luis;Pérez-camino, María Carmen;Burgos-Morón, Estefanía;López-Lázaro, Miguel;Vazquez-Cueto, Carmen Maria:
Wild olive oil intake reduces blood pressure and improves antioxidant capacity and endothelial function in nitric oxide-depleted hypertensive rats. Journal of Physiology and Biochemistry. 2016. Vol: 72. Núm: Suppl 1. Pág. S102-S102.
Vazquez-Cueto, Carmen Maria;Ruiz-Armenta, Maria Victoria;Blanca-Lobato, Antonio Jesus;Miguel-Carrasco, Jose Luis;Pérez-camino, María Carmen;Burgos-Morón, Estefanía;López-Lázaro, Miguel;Mate-Barrero, Alfonso:
Efecto del aceite de acebuche sobre la hipertensión arterial y la actividad antioxidante sistémica. Hipertensión y Riesgo Vascular. 2016. Vol: 33. Núm: Espec Congr. Pág. 3-3.
Calderón-Montaño, José Manuel;Burgos-moron, Estefania;Orta-Vázquez, Manuel Luis;García-domínguez, Irene;López-Lázaro, Miguel:
Bufalin is a steroid receptor coactivator inhibitor-letter. Cancer Research. 2015. Vol: 75. Núm: 6. 10.1158/0008-5472.CAN-14-0398.
Torres-valencia, Jm;Cerda-garcía-rojas, Ca;Joseph-nathan, P;Motilva-Sánchez, Virginia;Manríquez-torres, J;García-Mauriño-Ruiz-Berdejo, Sofia;López-Lázaro, Miguel;Zbakh, H;Calderón-Montaño, José Manuel;Gómez-hurtado, Ma;Gayosso-de-lucio , Jo:
Antiproliferative Activity of seco-Oxacassanes from Acacia schaffneri. Natural Product Communications. 2015. Vol: 10. Núm: 6. Pág. 853-856. 10.1016/j.celrep.2015.12.032.. .
López-Lázaro, Miguel:
Two preclinical tests to evaluate anticancer activity and to help validate drug candidates for clinical trials. Oncoscience. 2015. Vol: 2. Núm: 2. Pág. 91-98. 10.18632/oncoscience.132.
Martin-Banderas, Lucia;Fernandez-Arevalo, Mercedes;Muñoz-Rubio, Inmaculada;Prados-Salazar, José Carlos;Alvarez-Fuentes, Josefa;Calderón-Montaño, José Manuel;López-Lázaro, Miguel;Arias-Mediano, Jose Luis;Leiva-Arrabal, María Del Carmen;Holgado-Villafuerte, Maria Angeles:
In vitro and in vivo evaluation of ¿9-tetrahidrocannabinol/PLGA nanoparticles for cancer chemotherapy. International Journal of Pharmaceutics. 2015. Vol: 487. Pág. 205-212.
López-Lázaro, Miguel:
The migration ability of stem cells can explain the existence of cancer of unknown primary site. Rethinking metastasis. Oncoscience. 2015. Vol: 2. Núm: 5. Pág. 467-475. 10.18632/oncoscience.159.
López-Lázaro, Miguel:
How many times should we screen a chemical library to discover an anticancer drug?. Drug Discovery Today. 2015. Vol: 20. Núm: 2. Pág. 167-169. 10.1016/j.drudis.2014.12.006.
Burgos-Morón, Estefanía;Calderón-Montaño, José Manuel;Orta-Vázquez, Manuel Luis;Mateos-Cordero, Santiago;López-Lázaro, Miguel:
Effect of DNA repair deficiencies on the cytotoxicity of resveratrol. WebmedCentral.com. 2015. Vol: 6. Núm: 5.
López-Lázaro, Miguel:
Cancer arises from stem cells: opportunities for anticancer drug discovery. Drug Discovery Today. 2015. Vol: 20. Núm: 11. Pág. 1285-1287. 10.1016/j.drudis.2015.09.006.
López-Lázaro, Miguel:
A simple and reliable approach for assessing anticancer activity in vitro . Current Medicinal Chemistry. 2015. Vol: 22. Núm: 11. Pág. 1324-1334. 10.2174/0929867322666150209150639.
López-Lázaro, Miguel:
Stem cell division theory of cancer. Cell Cycle. 2015. Vol: 14. Núm: 16. Pág. 2547-2548. 10.1080/15384101.2015.1062330.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Guillén-Mancina, Emilio;López-Lázaro, Miguel:
Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer therapy? . Investigational New Drugs. 2015. Vol: 33. Núm: 3. 10.1007/s10637-014-0204-4.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Orta-Vázquez, Manuel Luis;López-Lázaro, Miguel:
Effect of DNA Repair Deficiencies on the Cytotoxicity of Drugs Used in Cancer Therapy - A Review . Current Medicinal Chemistry. 2014. Vol: 21. Núm: 30. Pág. 3419-3454.
Orta-Vázquez, Manuel Luis;Helleday, Thomas;Hoglund, Andreas ;Calderón-Montaño, José Manuel;Domínguez-García, Inmaculada;Burgos-Morón, Estefanía;Visnes, Torkild ;Pastor-Carrillo, Nuria María;Strom, Cecilia ;López-Lázaro, Miguel:
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2¿deoxycytidine lesions.. Nucleic Acids Research. 2014. Vol: 41. Núm: 14. Pág. 9108-9120.
Leon-Gonzalez, Antonio Jose;Manson, Margaret;López-Lázaro, Miguel;Navarro-Zafra, Inmaculada;Martín-Cordero, Carmen:
Induction of Apostosis and Cell Cycle Arrest in Human Colon Carcinoma Cells by Corema album leaves. Natural Product Communications. 2014. Vol: 9. Núm: 1. Pág. 55-56.
Leon-Gonzalez, Antonio Jose;Acero, Nuria;Muñoz-mingarro, Dolores;López-Lázaro, Miguel;Martín-Cordero, Carmen:
Cytotoxic activity of hirsutanone, a diarylheptanoid isolated from Alnus glutinosa leaves. Phytomedicine. 2014. Vol: 15. Núm: 21. Pág. 866-870. 10.1016/j.phymed.2014.01.008.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Orta-Vázquez, Manuel Luis;Navas, Lola E.;García-domínguez, Irene;López-Lázaro, Miguel:
Evaluating the cancer therapeutic potential of cardiac glycosides. BioMed Research International. 2014. Vol: 2014. Pág. 9-9. http://dx.doi.org/10.1155/2014/794930.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;López-Lázaro, Miguel:
Comment on `Quiescence and yH2AX in neuroblastoma are regulated by Ouabain/ Na,K-ATPase¿: ouabain and cancer. British Journal of Cancer. 2013. Vol: 108. Núm: 10. Pág. 2189-2190. 10.1038/bjc.2013.234.
Vega-Perez, Jose Manuel;Palo-Nieto, Juan Carlos;Vega-Holm, Margarita;Góngora-vargas, Purificación;Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;López-Lázaro, Miguel;Iglesias-Guerra, Fernando:
Aziridines from alkenyl-beta-D-galactopyranoside derivatives: Stereoselective synthesis and in vitro selective anticancer activity. European Journal of Medicinal Chemistry. 2013. Vol: 70. Pág. 380-392. 10.1016/j.ejmech.2013.10.020.
Orta-Vázquez, Manuel Luis;Calderón-Montaño, José Manuel;Domínguez-García, Inmaculada;Pastor-Carrillo, Nuria María;Burgos-Morón, Estefanía;López-Lázaro, Miguel;Cortés-Benavides, Felipe;Mateos-Cordero, Santiago;Helleday, Thomas :
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair. Nucleic Acids Research. 2013. Vol: 41. Núm: 11. Pág. 5827-5836. 10.1093/nar/gkt270.
Truchado, Pilar;Tomás-barberán, Francisco A.;López-Lázaro, Miguel:
Phenolic acids, flavonols and anthocyanins in Corema album (L.) D. Don berries. Journal of Food Composition and Analysis. 2013. Vol: 29. Pág. 58-63. http://dx.doi.org/10.1016/j.jfca.2012.10.003,.
Leon-Gonzalez, Antonio Jose;Truchado, Pilar;Tomás-barberán, Francisco A.;López-Lázaro, Miguel;Diaz-Antunez-Barradas, Maria Cruz;Martín-Cordero, Carmen:
Phenolic acids, flavonols and anthocyanins in Corema album (L.) D. Don berries. Journal of Food Composition and Analysis. 2013. Vol: 29. Pág. 58-63. http://dx.doi.org/10.1016/j.jfca.2012.10.003.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Orta-Vázquez, Manuel Luis;Mateos-Cordero, Santiago;López-Lázaro, Miguel:
A Hydroalcoholic Extract from the Leaves of Nerium oleander Inhibits Glycolysis and Induces Selective Killing of Lung Cancer Cells. Planta Medica. 2013. Vol: 79 . Núm: 12. Pág. 1017-1023. 10.1055/s-0032-1328715.
López-Lázaro, Miguel:
Cytotoxic activity of dihydrochalcones isolated from Corema album leaves against HT-29 colon cancer cells. Natural Product Communications. 2013. Vol: 8. Núm: 9. Pág. 1255-1256.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Martínez-sánchez, Sara María;López-Lázaro, Miguel:
Vitamin C and the Red Wine Polyphenol Resveratrol - but not Curcumin and the Glycolysis Inhibitors 2- Deoxyglucose, Dichloroacetate and 3-Bromopyruvat. WebmedCentral.com. 2013. Vol: 4. Núm: 7. WMC004329.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Martínez-sánchez, Sara María;López-Lázaro, Miguel:
Dichloroacetate, 2-Deoxyglucose and a Hydroalcoholic Extract from the Skin of the Fruit of Solanum melongena (Aubergine) Induce Selective Anticancer A. WebmedCentral.com. 2013. Vol: 4. Núm: 7. WMC004326.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;López-Lázaro, Miguel:
The in vivo antitumor activity of cardiac glycosides in mice xenografted with human cancer cells is probably an experimental artifact. Oncogene. 2013. 10.1038/onc.2013.229.
Leon-Gonzalez, Antonio Jose;López-Lázaro, Miguel:
Cytotoxic Activity of Dihydrochalcones Isolated from Corema album Leaves agains HT-29 Colon Cancer Cells. Natural Product Communications. 2013. Vol: 8. Núm: 9. Pág. 1255-1256.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;López-Lázaro, Miguel:
The Cardiac Glycosides Digitoxin, Digoxin and Ouabain Induce a Potent Inhibition of Glycolysis in Lung Cancer Cells. WebmedCentral.com. 2013. Vol: 4. Núm: 7. WMC004323.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Orta-Vázquez, Manuel Luis;Pastor-Carrillo, Nuria María;Austin, Caroline;Mateos-Cordero, Santiago;López-Lázaro, Miguel:
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cel. Toxicology Letters. 2013. Vol: 222. Núm: 1. Pág. 64-71. 10.1016/j.toxlet.2013.07.007.
Tena, J;Burgos-Morón, Estefanía;Calderón-Montaño, José Manuel;Sanz, I;Sainz, J;López-Lázaro, Miguel:
Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiologica. WebmedCentral.com. 2013. 2046-1690.
Leon-Gonzalez, Antonio Jose;López-Lázaro, Miguel;Espartero-Sanchez, Jose Luis;Martín-Cordero, Carmen:
Cytotoxic Activity of Dihidrochalcones isolted from Corema album leaves against HT-29 Colon Cancer Cells. Natural Product Communications. 2013. Vol: 8. Núm: 9. Pág. 1255-1256.
Calderón-Montaño, José Manuel;Madrona-Mojarro, Andrés;Burgos-Morón, Estefanía;Orta-Vázquez, Manuel Luis;Espartero-Sanchez, Jose Luis;López-Lázaro, Miguel:
Selective cytotoxic activity of new lipophilic hydroxytyrosol alkyl ether derivatives. Journal of Agricultural and Food Chemistry. 2013. Vol: 61. Núm: 21. Pág. 5046-5053. 10.1021/jf400796p.
Garcia-Gimenez, Maria Dolores;López-Lázaro, Miguel:
Antioxidant and cytotoxic activities of Sideritis perezlarae (Borja) Rosello, Stübing and Peris. Natural Product Research. 2013. Vol: 27. Núm: 17. Pág. 1602-1606. Doi: 10.108/:14786419.2012.740031.
Vega-Perez, Jose Manuel;Palo-Nieto, Juan Carlos;Periñán-Domínguez, Ignacio;Vega-Holm, Margarita;Calderón-Montaño, José Manuel;López-Lázaro, Miguel;Iglesias-Guerra, Fernando:
Stereoselective Dihydroxylation Reaction of Alkenyl ß-D-Hexopyranosides: A Methodology for the Synthesis of Glycosylglycerol Derivatives and 1-O-Acyl-. European Journal Of Organic Chemistry. 2012. Vol: 2012. Núm: 6. Pág. 1237-1252. 10.1002/ejoc.201101539.
Vega-Perez, Jose Manuel;Iglesias-Guerra, Fernando;Periñán-Domínguez, Ignacio;Argandoña-Bertran, Montserrat;Vega-Holm, Margarita;Palo-Nieto, Juan Carlos;Burgos-Morón, Estefanía;López-Lázaro, Miguel;Vargas-Macias, Carmen;Nieto-Gutiérrez, Joaquín José:
Isoprenyl-thiourea and urea derivatives as new farnesyl diphosphate analogues. Synthesis and in vitro antimicrobial and citotoxic activities. European Journal of Medicinal Chemistry. 2012. Vol: 58. Pág. 591-612. 10.1016/j.ejmech.2012.10.042.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Orta-Vázquez, Manuel Luis;Pastor-Carrillo, Nuria María;Pérez-Guerrero, Concepción;Austin, Caroline A.;Mateos-Cordero, Santiago;López-Lázaro, Miguel:
Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death. Pharmacological Reports. 2012. Vol: 64. Núm: 6. Pág. 1515-1525.
Martín-Cordero, Carmen;Leon-Gonzalez, Antonio Jose;Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;López-Lázaro, Miguel:
Pro-oxidant natural products as anticancer agents. Current Drug Targets. 2012. Vol: 13. Núm: 8. Pág. 1006-1028.
Burgos-Morón, Estefanía;Calderón-Montaño, José Manuel;Orta-Vázquez, Manuel Luis;Pastor-Carrillo, Nuria María;Pérez-Guerrero, Concepción;Austin, C;Mateos-Cordero, Santiago;López-Lázaro, Miguel:
The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I- and II-DNA Complexes in Cells. Journal of Agricultural and Food Chemistry. 2012. Vol: Epub ahead of print.
Leon-Gonzalez, Antonio Jose;Mateos, Raquel;Ramos-Rivero, Sonia;Martín-Arribas, Maria Angeles;Sarriá-Ruiz, Beatriz;Martín-Cordero, Carmen;López-Lázaro, Miguel;Bravo-Clemente, Laura;Goya-Suárez, Luis:
Chemo-protective activity and characterization of phenolic extracts from Corema album. Food Research International. 2012. Vol: 49. Pág. 728-738. http://dx.doi.org/10.1016/j.foodres.2012.09.016.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Pérez-Guerrero, Concepción;López-Lázaro, Miguel:
A REVIEW ON THE DIETARY FLAVONOID KAEMPFEROL. Mini-Reviews in Medicinal Chemistry. 2011. Vol: 11. Núm: 4. Pág. 298-344.
Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Pérez-Guerrero, Concepción;Salvador-Bofill, Francisco Javier;Robles-Frias, Antonio;López-Lázaro, Miguel:
ROLE OF THE INTRACELLULAR PH IN THE METABOLIC SWITCH BETWEEN OXIDATIVE PHOSPHORYLATION AND AEROBIC GLYCOLYSIS - RELEVANCE TO CANCER. WebmedCentral.com. 2011. Vol: 2. Núm: 3.
López-Lázaro, Miguel;Calderón-Montaño, José Manuel;Burgos-Morón, Estefanía;Austin-,Caroline A.:
GREEN TEA CONSTITUENTS (-)-EPIGALLOCATECHIN-3-GALLATE (EGCG) AND GALLIC ACID INDUCE TOPOISOMERASE I- AND TOPOISOMERASE II-DNA COMPLEXES IN CELLS MEDIA. Mutagenesis. 2011. Vol: 26. Núm: 4. Pág. 489-498.
Burgos-Morón, Estefanía;Calderón-Montaño, José Manuel;Pérez-Guerrero, Concepción;Perez-Guerrero,Concepcion;López-Lázaro, Miguel:
MORE RESEARCH IS NEEDED TO ESTABLISH THE BENEFIT-RISK PROFILE OF CURCUMIN. International Journal of Cancer. 2011. Vol: 128. Núm: 1. Pág. 245-246.
López-Lázaro, Miguel;Willmore-,Elaine;Austin-,Caroline A.:
THE DIETARY FLAVONOIDS MYRICETIN AND FISETIN ACT AS DUAL INHIBITORS OF DNA TOPOISOMERASES I AND II IN CELLS. Mutation research. Genetic toxicology and environmental mutagenesis (Print). 2010. Vol: 696. Núm: 1. Pág. 41-47.
Burgos-Morón, Estefanía;Calderón-Montaño, José Manuel;Salvador-Bofill, Francisco Javier;Robles-Frias, Antonio;López-Lázaro, Miguel:
THE DARK SIDE OF CURCUMIN.. International Journal of Cancer. 2010. Vol: 126. Núm: 7. Pág. 1771-1775.
López-Lázaro, Miguel:
A NEW VIEW OF CARCINOGENESIS AND AN ALTERNATIVE APPROACH TO CANCER THERAPY. Molecular Medicine. 2010. Vol: 16. Núm: 3-4. Pág. 144-153.
Leon-Gonzalez, Antonio Jose;López-Lázaro, Miguel;Ayuso-, Mª Jesus:
ANTIRADICAL ACTIVITY OF COREMA ALBUM L. UNRIPE BERRIES. Methods and Findings in Experimental and Clinical Pharmacology . 2009. Vol: 31. Núm: A. Pág. 88-88.
López-Lázaro, Miguel:
ROLE OF OXYGEN IN CANCER: LOOKING BEYOND HYPOXIA.. Anti-Cancer Agents in Medicinal Chemistry. 2009. Vol: 9. Núm: 5. Pág. 517-525.
Burgos-Morón, Estefanía;Periñán-Domínguez, Ignacio;Vega-Perez, Jose Manuel;Iglesias-Guerra, Fernando;Ayuso-González, María Jesús;López-Lázaro, Miguel:
CYTOTOXIC ACTIVITY OF FARNESYL DIPHOSPHATE ANALOGUES HT-29 HUMAN COLON CANCER CELLS. Methods and Findings in Experimental and Clinical Pharmacology . 2009. Vol: 31. Núm: SA. Pág. 97-97.
López-Lázaro, Miguel:
DISTRIBUTION AND BIOLOGICAL ACTIVITIES OF THE FLAVONOID LUTEOLIN. Mini-Reviews in Medicinal Chemistry. 2009. Vol: 9. Núm: 1. Pág. 31-59.
Garcia-Gimenez, Maria Dolores;De La Puerta, Rocio;Fernandez-Arche, Maria Angeles;Saenz-Rodriguez, Maria Teresa;López-Lázaro, Miguel:
CYTOTOXIC ACTIVITY ON HT-29 HUMAN COLON ADENOCARCINOMA CELL LINE OF TRIGUERO ASPARAGUS (ASPARAGUS OFFICINALIS L.). Methods and Findings in Experimental and Clinical Pharmacology . 2009. Vol: 31. Núm: A. Pág. 97-97.
López-Lázaro, Miguel:
DIGOXIN, HIF-1, AND CANCER.. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2009. Vol: 106. Núm: 9. Pág. 26-26.
López-Lázaro, Miguel:
ANTICANCER AND CARCINOGENIC PROPERTIES OF CURCUMIN: CONSIDERATIONS FOR ITS CLINICAL DEVELOPMENT AS A CANCER CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENT. Molecular Nutrition & Food Research. 2008. Vol: 52 Suppl 1. Pág. S103-S127.
Leon-Gonzalez, Antonio Jose;López-Lázaro, Miguel;Ayuso-, Mª Jesus;Toro-Sainz, María Victoria:
CYTOTOXIC ACTIVITY OF EXTRACTS FROM PHARMACOLOGICALLY ACTIVE PLANTS. Methods and Findings in Experimental and Clinical Pharmacology . 2008. Vol: 30. Núm: 2. Pág. 121-121.
López-Lázaro, Miguel:
THE WARBURG EFFECT: WHY AND HOW DO CANCER CELLS ACTIVATE GLYCOLYSIS IN THE PRESENCE OF OXYGEN?. Anti-Cancer Agents in Medicinal Chemistry. 2008. Vol: 8. Núm: 3. Pág. 305-312.
López-Lázaro, Miguel;Willmore-,E;Elliott-,Sarah L.;Austin-,Caroline A.:
SELENITE INDUCES TOPOISOMERASE I AND II-DNA COMPLEXES IN K562 LEUKEMIA CELLS. International Journal of Cancer. 2008. Vol: 123. Núm: 9. Pág. 2217-2221.
López-Lázaro, Miguel;Willmore-,Elaine;Austin-,Caroline A.:
CURCUMIN INDUCES HIGH LEVELS OF TOPOISOMERASE I- AND II DNA COMPLEXES IN K562 LEUKEMIA CELLS. Journal of Natural Products. 2007. Vol: 70. Núm: 12. Pág. 1884-1888.
López-Lázaro, Miguel:
EXCESSIVE SUPEROXIDE ANION GENERATION PLAYS A KEY ROLE IN CARCINOGENESIS.. International Journal of Cancer. 2007. Vol: 120. Núm: 6. Pág. 1378-1380.
López-Lázaro, Miguel:
DIGITOXIN AS AN ANTICANCER AGENT WITH SELECTIVITY FOR CANCER CELLS: POSSIBLE MECHANISMS INVOLVED. Expert Opinion On Therapeutic Targets. 2007. Vol: 11. Núm: 8. Pág. 1043-1053.
López-Lázaro, Miguel;Willmore-,Simon;Austin-,Caroline A.:
CELLS LACKING DNA TOPOISOMERASE II BETA ARE RESISTANT TO GENISTEIN. Journal of Natural Products. 2007. Vol: 70. Núm: 5. Pág. 763-767.
López-Lázaro, Miguel:
WHY DO TUMORS METASTASIZE?. Cancer Biology & Therapy. 2007. Vol: 6. Núm: 2. Pág. 141-144.
López-Lázaro, Miguel:
DUAL ROLE OF HYDROGEN PEROXIDE IN CANCER: POSSIBLE RELEVANCE TO CANCER CHEMOPREVENTION AND THERAPY. Cancer Letters. 2007. Vol: 252. Núm: 1. Pág. 1-8.
López-Lázaro, Miguel:
HIF-1: HYPOXIA-INDUCIBLE FACTOR OR DYSOXIA-INDUCIBLE FACTOR?. The FASEB Journal. 2006. Vol: 20. Núm: 7. Pág. 828-832.
López-Lázaro, Miguel:
HYPOXIA-INDUCIBLE FACTOR 1 AS A POSSIBLE TARGET FOR CANCER CHEMOPREVENTION. Cancer Epidemiology, Biomarkers & Prevention. 2006. Vol: 15. Núm: 12. Pág. 2332-2335.
López-Lázaro, Miguel:
GRANULOCYTE COLONY-STIMULATING FACTOR (G-CSF): A NOVEL ANTICANCER THERAPY BASED ON THE UNIVERSAL DYNAMICS OF TUMOR GROWTH?. Experimental Oncology. 2006. Vol: 28. Núm: 3. Pág. 249-251.
López-Lázaro, Miguel;Azrak-,Sami S.;Ayuso-González, María Jesús;Cortés-Benavides, Felipe;Austin-,Caroline A.:
DIGITOXIN, AT CONCENTRATIONS COMMONLY FOUND IN THE PLASMA OF CARDIAC PATIENTS, ANTAGONIZES ETOPOSIDE AND IDARUBICIN ACTIVITY IN K562 LEUKEMIA CELLS. Leukemia Research. 2006. Vol: 30. Núm: 7. Pág. 895-898.
López-Lázaro, Miguel:
DOES HYPOXIA REALLY CONTROL TUMOR GROWTH?. Cellular Oncology. 2006. Vol: 28. Núm: 5-6. Pág. 327-329.
López-Lázaro, Miguel;Pastor-Carrillo, Nuria María;Azrak-,Sami S.;Ayuso-González, María Jesús;Austin-,Caroline A.;Cortés-Benavides, Felipe:
DIGITOXIN INHIBITS THE GROWTH OF CANCER CELL LINES AT CONCENTRATIONS COMMONLY FOUND IN CARDIAC PATIENTS.. Journal of Natural Products. 2005. Vol: 68. Núm: 11. Pág. 1642-1645.
Berrougui-,Hicham;López-Lázaro, Miguel;Martín-Cordero, Carmen;Mamouchi-,Mohamed;Hmamouchi M,-Ettaib,Abd;Ettaib-,Abdelkader;Berrougui-,Hichan;Herrera-, María Dolores;Herrera-Gonzalez, Mª Dolores:
CYTOTOXIC ACTIVITY OF METHANOLIC EXTRACT AND TWO ALKALOIDS EXTRACTED FROM SEEDS OF PEGANUM HARMALA L.. Journal of Natural Remedies. 2005. Vol: 5. Núm: 1. Pág. 41-45.
Ayuso-González, María Jesús;Gálvez-Peralta, Marina;López-Lázaro, Miguel;Martín-Cordero, Carmen:
CITOTOXICIDAD DE PLANTAGO MAJOR L. Publicación Periódica Errónea. 2004. Pág. 19-22.
Pastor-Carrillo, Nuria María;Baos-Sendarrubias, Raquel;López-Lázaro, Miguel;Jovani-Tarrida, Roger;Tella-Escobedo, Jose Luis;Hajji-, Nabil;Hiraldo-Cano, Fernando;Cortés-, Felipe:
A 4 YEAR FOLLOW-UP ANALYSIS OF GENOTOXIC DAMAGE IN BIRDS OF THE DONANA AREA (SOUTH WEST SPAIN) IN THE WAKE OF THE 1998 MINING WASTE SPILL. Mutagenesis. 2004. Vol: 19. Núm: 1. Pág. 61-65.
López-Lázaro, Miguel;Gálvez-Peralta, Marina;Ayuso-González, María Jesús:
CURCUMIN AS DNA-TOPOISOMERASE II POISON. Methods and Findings in Experimental and Clinical Pharmacology . 2003. Vol: 25. Núm: SUPP. Pág. 117-117.
Martín-Cordero, Carmen;López-Lázaro, Miguel;Gálvez-Peralta, Marina;Ayuso-González, María Jesús:
CURCUMIN AS A DNA TOPOISOMERASE II POISON. Journal of Enzyme Inhibition and Medicinal Chemistry. 2003. Vol: 18. Núm: 6. Pág. 505-509.
Caballero-,E;Medarde-,Manuel;López-Lázaro, Miguel;Ayuso-González, María Jesús:
SYNTHESIS AND CYTOTOXIC ACTIVITY OF DIFFERENT OPEN INDOLOCARBAZOLE ALKALOID ANALOGUES. Bioorganic & Medicinal Chemistry. 2003. Vol: 11. Núm: 16. Pág. 3413-3421.
Cortés-Benavides, Felipe;Gálvez-Peralta, Marina;Martín-Cordero, Carmen;López-Lázaro, Miguel;Ayuso-González, María Jesús:
CYTOTOXIC EFFECT OF PLANTAGO SPP. ON CANCER CELL LINES. Journal of Ethnopharmacology. 2003. Vol: 88. Núm: 2-3. Pág. 125-130.
Cortés-Benavides, Felipe;López-Lázaro, Miguel;Pastor-Carrillo, Nuria María;Martín-Cordero, Carmen;Ayuso-González, María Jesús;Toro-Sainz, María Victoria:
ANTI-TUMOUR ACTIVITY OF DIGITALIS PURPUREA L. SUBSP HEYWOODII. Planta Medica. 2003. Vol: 69. Núm: 8. Pág. 701-704.
López-Lázaro, Miguel:
FLAVONOIDS AS ANTICANCER AGENTS: STRUCTURE-ACTIVITY RELATIONSHIP STUDY. Current Medicinal Chemistry. Anti-Cancer Agents. 2002. Vol: 2. Núm: 6. Pág. 691-714.
López-Lázaro, Miguel;Martín-Cordero, Carmen;Toro-Sainz, María Victoria;Ayuso-González, María Jesús:
FLAVONOIDS AS DNA TOPOISOMERASE I POISONS. Journal of Enzyme Inhibition and Medicinal Chemistry. 2002. Vol: 17. Núm: 1. Pág. 25-29.
Gálvez-Peralta, Marina;López-Lázaro, Miguel;Toro-Sainz, María Victoria;Ayuso-González, María Jesús:
FLAVONOIDS AS DNA TOPOISOMERASE POISONS.. Anticancer Research: International Journal of Cancer Research and Treatment. 2001. Vol: 21. Núm: 3. Pág. 1546-1547.
Martín-Cordero, Carmen;López-Lázaro, Miguel;Ayuso-González, María Jesús:
CYTOTOXIC COMPOUNDS FROM ANNONACEUS SPECIES AS DNA TOPOISOMERASE I POISONS. Anticancer Research: International Journal of Cancer Research and Treatment. 2001. Vol: 21. Núm: 5. Pág. 3493-3497.
Pastor-Carrillo, Nuria María;López-Lázaro, Miguel;Tella-Escobedo, Jose Luis;Baos-Sendarrubias, Raquel;Gonzalez-Forero, Manuela;Hiraldo-Cano, Fernando;Cortés-, Felipe:
DNA DAMAGE IN BIRDS AFTER THE MINING WASTE SPILL IN SOUTHWESTERN SPAIN: A COMET ASSAY EVALUATION.. Journal of Environmental Pathology, Toxicology and Oncology. 2001. Vol: 20. Núm: 4. Pág. 317-24.
Pastor-Carrillo, Nuria María;López-Lázaro, Miguel;Tella-Escobedo, Jose Luis;Baos-Sendarrubias, Raquel;Hiraldo-Cano, Fernando;Cortés-,F.:
ASSESSMENT OF GENOTOXIC DAMAGE BY THE COMET ASSAY IN WHITE STORKS (CICONIA CICONIA) AFTER THE DONANA ECOLOGICAL DISASTER. Mutagenesis. 2001. Vol: 16. Núm: 3. Pág. 219-223.
López-Lázaro, Miguel;Martín-Cordero, Carmen;Cortés-Benavides, Felipe;Piñero-Bustamante, Joaquín;Ayuso-González, María Jesús:
CYTOTOXIC ACTIVITY OF FLAVONOIDS AND EXTRACTS FROM RETAMA SPHAEROCARPA BOISSIER. Zeitschrift für Naturforschung. Section C: Journal of Biosciences. 2000. Vol: 55. Núm: 1-2. Pág. 40-43.
Martín-Cordero, Carmen;Espartero-Sanchez, Jose Luis;López-Lázaro, Miguel;Ayuso-González, María Jesús:
RETAMATRIOSIDE, A NEW FLAVONOL TRIGLYCOSIDE FROM RETAMA SPHAEROCARPA. Journal of Natural Products. 2000. Vol: 63. Núm: 2. Pág. 248-250.
López-Lázaro, Miguel;Ayuso-González, María Jesús:
CYTOTOXIC ACTIVITY OF ISOLATED COMPOUNDS FROM ANNONACEAE SPECIES. Methods and Findings in Experimental and Clinical Pharmacology . 2000. Vol: 22. Núm: 6. Pág. 496-496.
Gálvez-Peralta, Marina;López-Lázaro, Miguel;Cortés-Benavides, Felipe;Ayuso-González, María Jesús:
CYTOTOXIC ACTIVITY OF CHLOROFORMIC EXTRACT OF PLANTAGO MAJOR L. CULTIVATED BY MICROPROPAGATION.. Methods and Findings in Experimental and Clinical Pharmacology . 2000. Vol: 22. Núm: 6. Pág. 501-501.
Martín-Cordero, Carmen;López-Lázaro, Miguel;Piñero-Bustamante, Joaquín;Ortiz-Sallés, Trinidad;Cortés-Benavides, Felipe;Ayuso-González, María Jesús:
GLUCOSYLATED ISOFLAVONES AS DNA TOPOISOMERASE II POISONS. Journal of Enzyme Inhibition. 2000. Vol: 15. Núm: 5. Pág. 455-460.
López-Lázaro, Miguel;Martín-Cordero, Carmen;Ayuso-González, María Jesús:
TWO NEW FLAVONOL GLYCOSIDES AS DNA TOPOISOMERASE I POISONS. Zeitschrift für Naturforschung. Section C: Journal of Biosciences. 2000. Vol: 55. Núm: 11-12. Pág. 898-902.
Martín-Cordero, Carmen;López-Lázaro, Miguel;Gil-Serrano, Antonio Miguel;Rodriguez-Carvajal, Miguel Angel;Ayuso-González, María Jesús:
NOVEL FLAVONOL GLYCOSIDE FROM RETAMA SPHAEROCARPA BOISSIER. Phytochemistry: the International Journal of Plant Chemistry, Plant Biochemistry and Molecular Biology. 1999. Vol: 51. Núm: 8. Pág. 1129-1131.
Pedraza-Cerbán, María Angeles;Gálvez-Peralta, Marina;Ayuso-González, María Jesús;Toro-Sainz, María Victoria;López-Lázaro, Miguel:
NEW FLAVONOLS GLYCOSIDES FROM RETAMA SPHAEROCARPA BOISSIER AS DNA TOPOISOMERASE POISONS.. Methods and Findings in Experimental and Clinical Pharmacology . 1999. Pág. 0-0.
Pedraza-Cerbán, María Angeles;Gálvez-Peralta, Marina;Ayuso-González, María Jesús;Toro-Sainz, María Victoria;López-Lázaro, Miguel:
CYTOTOXIC ACTIVITY OF ISLATED COMPOUNDS FROM ANNONACEAE SPECIES. Methods and Findings in Experimental and Clinical Pharmacology . 1999. Pág. 0-0.
Pedraza-Cerbán, María Angeles;Gálvez-Peralta, Marina;Ayuso-González, María Jesús;Toro-Sainz, María Victoria;López-Lázaro, Miguel:
CYTOTOXIC ACTIVITY OF CHLOROFORMIC EXTRACT OF PLANTAGO MAJOR L. CULTIVATED BY MICROPROPAGATION.. Methods and Findings in Experimental and Clinical Pharmacology . 1999. Pág. 0-0.
López-Lázaro, Miguel;Martín-Cordero, Carmen;Iglesias-Guerra, Fernando;Ayuso-González, María Jesús:
AN ISOFLAVONE GLUCOSIDE FROM RETAMA SPHAEROCARPA BOISSIER. Phytochemistry: the International Journal of Plant Chemistry, Plant Biochemistry and Molecular Biology. 1998. Vol: 48. Núm: 2. Pág. 401-402.