MARIA DE LAS MERCEDES DELGADO VALVERDE

Categoría
Profesor Asociado CIS Interino

Contacto

Correo electrónico

Departamento

Área
Microbiología

Investigación

Grupo de investigación

RESISTENCIA A ANTIMICROBIANOS (RESISTENCIA A ANTIMICROBIANOS)

Proyectos y contratos de investigación

Optimización de dosificación de amoxicilina-clavulánico mediante modelo farmacodinámico en infecciones por Escherichia coli: papel de los mecanismos d (PI22/01663 - Investigador Principal Joven)
Seguimiento de Brotes de Klebsiella Pneumoniae Productor de Kpc-3 Mediante Secuenciación Masiva: Eficacia Frente A Técnicas de Tipado Convencionales. (PI-0221-2017 - Investigador Principal Joven)
Efecto de los transportadores en la actividad de fosfomicina in vitro e in vivo: Optimización del ensayo de sensibilidad in vitro y caracterización de (PI19/01645 - Investigador/a)

Asistencia a congresos

Arroyo-muñoz, Francisco-javier;González-caro, María-dolores;Fernández-Castillo, Rafael-jesús;Cantón-bulnes, María-luisa;Portillo-calderón, Irene;Delgado-valverde, Mercedes;Garnacho-Montero, Jose:
Evaluación de apósito de clorhexidina vs apósito simple de poliuretano en la colonización epitelial de pacientes de UCI. Comunicación en congreso. XLVIII Congreso Nacional de la SEEIUC. Palacio de Ferias y Congresos de Málaga (Fycma). Málaga. 2023
Pérez-Palacios, Patricia;Gual De Torrella, Ana;López-Cerero, Lorena;Delgado-valverde, Mercedes;Recacha, Esther;Pascual-Hernandez, Alvaro:
Characterisation and evolution of an IncR-type plasmid carrying blaVIM-1 and blaCTX-M-15 associated with hospital dissemination of Klebsiella pneumoni. Poster en Congreso. 33rd European Congress of Clinical Microbiology and Infectious Diseases. Copenhagen, Dinamarca. 2023
Recacha, Esther;Delgado-valverde, Mercedes;López-Cerero, Lorena;Pascual-Hernandez, Alvaro:
Análisis comparativo del entorno genético de plásmidos portadores de blaKPC-3 en aislados de K. pneumoniae del clon emergente ST147 y otros clones. Poster en Congreso. 1er Congreso SAMICEI. Málaga. 2022
Machuca-Bárcena, Jesús;Rodríguez-bernal, David;López-Cerero, Lorena;Esteban-moreno, M.a.;Fernandez-Cuenca, Felipe;Delgado-valverde, Mercedes;López-Hernández, Inmaculada;Sánchez-Yebra-Romera, Waldo Eugenio;Pascual-Hernandez, Alvaro:
Caracterización microbiológica de brote causado por Klebsiella pneumoniae productor de NDM-7 en Almería. Comunicación en congreso. XXXII SAMPAC Reunión de la Sociedad Andaluza de Microbiología y Parasitología Clínica. SEVILLA. 2019
M. Natera, Alejandra;Rodríguez-gómez, Jorge;Romero-saldaña, Manuel;López-Cerero, Lorena;Delgado-valverde, Mercedes;Martinez-Martinez, Luis;Torre-Cisneros J;Pérez-Nadales E;Recio-rufián, Manuel;Rodríguez-López, Fernando Carlos;Frutos-adame, Azahara;Cano A;Castón, JJ;Natera C;Causse-Del Rio, Manuel:
Cinética temporal de la cuantificación de la colonización intestinal en portadores de Klebsiella pneumoniae productora de carbapenemasa KPC: riesgo de. Poster en Congreso. XXI Congreso de la SAEI 2019. Sevilla. 2019
M. Natera, Alejandra;López-Cerero, Lorena;Delgado-valverde, Mercedes;Martinez-Martinez, Luis;Torre-Cisneros J;Pérez-Nadales E;Recio-rufián, Manuel;Cano A;Rodríguez-López, Fernando Carlos;Castón, JJ;Rodríguez-gómez, Jorge;Causse-Del Rio, Manuel;Romero-saldaña, Manuel:
Bacterial load as risk factor for colonization, infection and mortality by carbapenemase producing Klebsiella pneumoniae : KLEBCOM Study. Poster en Congreso. Bacterial load as risk factor for colonization, infection and mortality by carbapenemase producing Klebsiella pneumoniae : KLEBCOM Study. Sevilla. 2019

Artículos publicados

Liébana-rodríguez, M;Portillo-calderón, Inés;Fernández-sierra , Ma;Delgado-valverde, Mercedes;Martin, Lina;Gutiérrez-Fernández, José:
Nosocomial outbreak caused by Serratia marcescens in a neonatology intensive care unit in a regional hospital. Analysis and improvement proposals. Enfermedades infecciosas y microbiologia clinica (English ed.). 2023. 10.1016/j.eimce.2023.04.019.
Delgado-valverde, Mercedes;Portillo-calderón, Inés;Alcalde, Manuel;Conejo-Gonzalo, Maria Carmen;Hidalgo-Diaz, Carmen;Del Toro-esperón, C;Pascual-Hernandez, Alvaro:
Activity of imipenem/relebactam and comparators against KPC-producing Klebsiella pneumoniae and imipenem-resistant Pseudomonas aeruginosa. European Journal of Clinical Microbiology & Infectious Diseases. 2023. 10.1007/s10096-023-04735-1.
Delgado-valverde, Mercedes;Portillo-calderón, Inés;Recacha, Esther;Pérez-Palacios, Patricia;Pascual-Hernandez, Alvaro:
In Vitro Activity of Cefiderocol Compared to Other Antimicrobials against a Collection of Metallo-Beta-Lactamase-Producing Gram-Negative Bacilli from . Microbiology Spectrum. 2023. Vol: 11. Núm: 3. 10.1128/spectrum.04936-22. Epub 2023 May 30.
Pérez-Palacios, Patricia;Delgado-valverde, Mercedes;Pascual-Hernandez, Alvaro;Fernandez-Cuenca, Felipe:
Transfer of plasmids harbouring blaOXA-48-like carbapenemase genes in biofilm-growing Klebsiella pneumoniae: Effect of biocide exposure. Microbiological Research. 2022. Vol: 254. https://doi.org/10.1016/j.micres.2021.126894.
Palacios, Zaira Raquel;Pascual-Hernandez, Alvaro;Delgado-valverde, Mercedes:
CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumonia e and Escherichia coli From All Spanish Provinces Reveals Interregional S. Frontiers in Microbiology. 2022. 10.3389/fmicb.2022.918362.
Delgado-valverde, Mercedes;Pérez-Palacios, Patricia;Pascual-Hernandez, Alvaro;Fernandez-Cuenca, Felipe:
In vitro activity of six biocides against carbapenemase-producing Klebsiella pneumoniae and presence of genes encoding efflux pumps. Enfermedades infecciosas y microbiologia clinica (English ed.). 2022. Vol: 40. Núm: 7. 10.1016/j.eimce.2021.05.016.
Delgado-valverde, Mercedes;Pérez-Palacios, Patricia;Pascual-Hernandez, Alvaro;Fernandez-Cuenca, Felipe:
Prevalence of the fimbrial operon mrkABCD, mrkA expression, biofilm formation and effect of biocides on biofilm formation in carbapenemase-producing K. International Journal of Antimicrobial Agents. 2022. Vol: 60. Núm: 4. https://doi.org/10.1016/j.ijantimicag.2022.106663.
López-Cerero, Lorena;Delgado-valverde, Mercedes;Rodríguez-Martínez, José Manuel;Rodriguez-Baño, Jesus;Pascual-Hernandez, Alvaro:
Higher prevalence of CTX-M-27-producing Escherichia coli belonging to ST131 clade C1 among residents of two long-term care facilities in Southern Spai. European Journal of Clinical Microbiology & Infectious Diseases. 2022. Vol: 41. Núm: 2. 10.1007/s10096-021-04380-6.
Delgado-valverde, Mercedes:
In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal (SUPERIOR and STEP . Journal of Antimicrobial Chemotherapy. 2022. Vol: 77. Núm: 11. 10.1093/jac/dkac298.
Delgado-valverde, Mercedes:
Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ICU Patients from Spain and Portugal (SUPERIOR and STEP Studies). Microbiology Spectrum. 2022. Vol: 10. Núm: 5. 10.1128/spectrum.02927-22.
López-Cerero, Lorena;Fernandez-Cuenca, Felipe;López-Hernández, Inmaculada;Delgado-valverde, Mercedes;Sánchez-Yebra-Romera, Waldo Eugenio;Pascual-Hernandez, Alvaro:
Molecular characterisation of an outbreak of NDM-7-producing Klebsiella pneumoniae reveals ST11 clone expansion combined with interclonal plasmid diss. International Journal of Antimicrobial Agents. 2022. Vol: 59. Núm: 4. 10.1016/j.ijantimicag.2022.106551.
Pérez-Palacios, Patricia;Delgado-valverde, Mercedes;Fernandez-Cuenca, Felipe;Pascual-Hernandez, Alvaro:
Co¿transfer of plasmid¿encoded bla carbapenemases genes and mercury resistance operon in high¿risk clones of Klebsiella pneumoniae. Applied Microbiology and Biotechnology. 2021. Vol: 105. Núm: 24. Pág. 9231-9242. 10.1007/s00253-021-11684-2.
Soria-Segarra, Carmen Gabriela;Delgado-valverde, Mercedes;SERRANO-GARCÍA, MARIA LUISA;López-Hernández, Inmaculada;Navarro-Mari, Jose Maria;Gutiérrez-Fernández, José:
Infections in patients colonized with carbapenem-resistant Gram-negative bacteria in a medium Spanish city. Revista Española de Quimioterapia. 2021. Vol: 34. Núm: 5. 10.37201/req/021.2021. Epub 2021 Jun 8.
Delgado-valverde, Mercedes;Rodriguez-Baño, Jesus:
Household acquisition and transmission of extended-spectrum b-lactamase (ESBL) -producing Enterobacteriaceae after hospital discharge of ESBL-positive. Clinical Microbiology and Infection. 2021. https://doi.org/10.1016/j.cmi.2020.12.024.
Merino, Vicente;Docobo-Pérez, Fernando Manuel;Valiente-Méndez, Adoración;Delgado-valverde, Mercedes;Pascual-Hernandez, Alvaro;Rodriguez-Baño, Jesus:
Population Pharmacokinetics of Piperacillin in Non-Critically Ill Patients with Bacteremia Caused by Enterobacteriaceae. Antibiotics. 2021. Vol: 10. Núm: 4. 10.3390/antibiotics10040348.
Delgado-valverde, Mercedes;Pascual-Hernandez, Alvaro;Fernandez-Cuenca, Felipe:
Mechanisms of Tolerance and Resistance to Chlorhexidine in Clinical Strains of Klebsiella pneumoniae Producers of Carbapenemase: Role of New Type II T. Toxins. 2020. Vol: 12. http://dx.doi.org/10.3390/toxins12090566.
Delgado-valverde, Mercedes:
Formulation, long-term physicochemical and microbiological stability of 15% topical resorcinol for hidradenitis suppurativa. European Journal of Hospital Pharmacy - Science and Practice. 2020. 10.1136/ejhpharm-2020-002534.
Delgado-valverde, Mercedes:
WGS characterization of MDR Enterobacterales with different ceftolozane/tazobactam susceptibility profiles during the SUPERIOR surveillance study in S. JAC-Antimicrobial Resistance. 2020.
Delgado-valverde, Mercedes:
Distinct epidemiology and resistance mechanisms affecting ceftolozane/tazobactam in Pseudomonas aeruginosa isolates recovered from ICU patients in Spa. Journal of Antimicrobial Chemotherapy. 2020. 10.1093/jac/dkaa430.
López-Hernández, Inmaculada;Delgado-valverde, Mercedes;Fernandez-Cuenca, Felipe;López-Cerero, Lorena;Pascual-Hernandez, Alvaro:
Carbapenemase-Producing Gram-Negative Bacteria in Andalusia, Spain, 2014¿2018. Emerging Infectious Diseases. 2020. https://doi.org/10.3201/eid2609.191772.
Delgado-valverde, Mercedes;Conejo-Gonzalo, Maria Carmen;Fernandez-Cuenca, Felipe;Pascual-Hernandez, Alvaro:
Activity of cefiderocol against high-risk clones of multidrug-resistant Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotro. Journal of Antimicrobial Chemotherapy. 2020. Vol: 75. Núm: 7. Pág. 1840-1849. https://doi.org/10.1093/jac/dkaa117.
Merino, Vicente;Delgado-valverde, Mercedes:
Physicochemical and microbiological stability of two news oral liquid formulations of clonidine hydrochloride for pediatric patients. Pharmaceutical Development and Technology. 2019. Núm: 11. https://doi.org/10.1080/10837450.2018.1514520.
Delgado-valverde, Mercedes:
Activity of ceftolozane/tazobactam against Pseudomonas aeruginosa and Enterobacterales isolates recovered from intensive care unit patients in Spain: . International Journal of Antimicrobial Agents. 2019. Vol: 53. Pág. 682-688. https://doi.org/10.1016/j.ijantimicag.2019.02.004.
Palacios, Zaira Raquel;Pascual-Hernandez, Alvaro;Rodriguez-Baño, Jesus;Delgado-valverde, Mercedes:
Impact of de-escalation on prognosis of patients with bacteraemia due to Enterobacteriaceae: a post-hoc analysis from a multicenter prospective cohort. Clinical Infectious Diseases. 2018. 10.1093/cid/ciy1032..
López-Cortés, Luis Eduardo;Rodriguez-Baño, Jesus;Delgado-valverde, Mercedes;Lupión-Mendoza, Carmen:
Targeted simplification versus antipseudomonal broad-spectrum betalactams in patients with bloodstream infections due to Enterobacteriaceae (SIMPLIFY). BMJ Open. 2017. Vol: 7. 10.1136/bmjopen-2016-015439.
Delgado-valverde, Mercedes;Causse-Del Rio, Manuel;Pascual-Hernandez, Alvaro;Rodriguez-Baño, Jesus;Reipi/geih-seimc Bacteraemia-mic , Group;Torres, Eva:
MIC of amoxicillin/clavulanate according to CLSI and EUCAST: discrepancies and clinical impact in patients with bloodstream infections due to Enterob. Journal of Antimicrobial Chemotherapy. 2017. Vol: 72. Núm: 5. Pág. 1478-1487. 10.1093/jac/dkw562.
Delgado-valverde, Mercedes;Causse-Del Rio, Manuel;Pascual-Hernandez, Alvaro;Gutiérrez-Gutiérrez, Belén;Torres, Eva;Rodriguez-Baño, Jesus:
Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project. Journal of Antimicrobial Chemotherapy. 2016. Vol: 71. Núm: 2. Pág. 521-530.
Torres, E;Delgado-valverde, Mercedes;Valiente, A;Pascual-Hernandez, Alvaro;Rodriguez-Baño, Jesus:
Impact of borderline minimum inhibitory concentration on the outcome of invasive infections caused by Enterobacteriaceae treated with ß-lactams: a sys. European Journal of Clinical Microbiology & Infectious Diseases. 2015. Vol: 34. Núm: 9. Pág. 1751-1758. 10.1007/s10096-015-2408-8..
López-Hernández, Inmaculada;Delgado-valverde, Mercedes;Batista-Diaz, Ninive;Pascual-Hernandez, Alvaro:
First report of linezolid dependence in methicillin-resistant Staphylococcus aureus.. Clinical Microbiology and Infection. 2015. Vol: 21. Núm: 7. Pág. 650.e1-650.e4. 10.1016/j.cmi.2015.03.012.
Delgado-valverde, Mercedes;Fernández-echauri, Pedro;Batista-díaz, Nínive;Pascual-Hernandez, Alvaro:
Variantes pequeñas de Staphylococcus aureus: utilidad de distintas pruebaspara su diagnóstico y estudio de sensibilidad. Enfermedades Infecciosas y Microbiología Clínica. 2014. Vol: 32. Núm: 2. Pág. 96-98. https://doi.org/10.1016/j.eimc.2013.06.005.
Delgado-valverde, Mercedes;Sojo-Dorado, Jesús;Pascual-Hernandez, Alvaro;Rodriguez-Baño, Jesus:
Clinical management of infections caused by multidrug-resistant Enterobacteriaceae. Therapeutic Advances in Infectious Disease. 2013. Vol: 1. Pág. 49-69.